Regular aerobic training improves insulin resistance but not pancreatic β-cells function in female patients with type 2 diabetes
محورهای موضوعی : Journal of Physical Activity and Hormones
Mohsen Omidi
1
(MS in exercise physiology, Marvdasht branch, Islamic Azad University, Marvdasht, Iran)
Mehrzad Moghadasi
2
(Associate professor in exercise physiology, Department of exercise physiology, Shiraz branch, Islamic Azad University, Shiraz, Iran)
کلید واژه: Insulin resistance, Aerobic training, Type 2 diabetes, Pancreatic β-cells function,
چکیده مقاله :
Aim: Pancreatic β-cells function and insulin sensitivity resistance were impaired in type 2 diabetes. Exercise training may improves these impairs, however, this is not well known. The aim of present study was to examine the effect of 8 weeks aerobic training on pancreatic β-cells function and insulin resistance in female patients with type 2 diabetes. Material & Methods: Twenty middle-aged women (age, 40 -50 years) with type 2 diabetes participated as the subject. The subjects were randomly assign to control group (n=10) or the training group (n=10). The subjects in the training group performed 30 to 45 min aerobic training on the treadmill with 60-75% of their maximum heart rate, 3 days a week for 8 weeks. The subjects in the control group were instructed to maintain their normal physical activity throughout the study. Results: The results indicated that fasting blood sugar, fasting insulin and insulin resistance index decrease in the training group compare to the control group (P<0.05); however, pancreatic β-cells function has no significant change after the intervention. Conclusion: In summary, it seems that aerobic training utilized in this study improves glucose entry into cells but it had not effective on pancreatic β-cells function.
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