Catalyst-free synthesis of aminothiazole derivatives in water

الموضوعات : Iranian Journal of Organic Chemistry

Mahboubeh Ghasemian Dazmiri ¹ , Narges Ghasemi ² , Annataj Noushin ³

1 -
2 -
3 -

تاريخ الإرسال : 27 الأربعاء , جمادى الأولى, 1444 تاريخ التأكيد : 27 الأربعاء , جمادى الأولى, 1444 تاريخ الإصدار : 03 الإثنين , محرم, 1444

الکلمات المفتاحية: Primary Amines, aminothiazole, Phosphonate, Phosphites, Activated acetylenic compound, Benzoylisothiocyanates,

ملخص المقالة :

Functionalized aminothiazole are generated from the reaction of dimethyl acetylenedicarboxylate, benzoylisothiocyanates, primary amines, hydrazonoyl chloride and triphenylphosphine in water. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.