A Simple and one-pot synthesis of imintriazole derivatives under Solvent-free conditions

الموضوعات : Iranian Journal of Organic Chemistry

Narges Ghasemi ¹ , Parvaneh Firoozi Khanghah ² , Mahboubeh Ghasemian Dazmiri ³

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تاريخ الإرسال : 08 الثلاثاء , شعبان, 1444 تاريخ التأكيد : 08 الثلاثاء , شعبان, 1444 تاريخ الإصدار : 10 الأربعاء , رجب, 1444

الکلمات المفتاحية: Solvent-free, One-pot reaction, Acid chlorides, Hydrazonoyl chloride, 3-amino-2-butanone,

ملخص المقالة :

An efficient synthesis of iminetriazole derivatives is described via an one-pot reaction between acid chlorides, 3-amino-2-butanone, primary amines and hydrazonoyl chloride under solvent-free conditions at room temperature in good yields. Also, the antimicrobial activity of some synthesized compounds proved by employing the disk diffusion test on Gram-positive and Gram-negative bacteria. This procedure has some benefits such as short reaction time, product with excellent yields, simple catalyst and products separation.