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  • تاثیر دوازده هفته تمرین تداومی و تناوبی روی برخی آدیپوکاین و هپاتوکاین ها و مقاومت به انسولین در موش های دیابتی نوع یک

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رقم المقالة : ASCIJ-2302-1466 (R1) زيارة : 355 الصفحة: 83 - 101

10.22034/ascij.2023.1979751.1466

نوع المخطوط: ابحاث

تاثیر دوازده هفته تمرین تداومی و تناوبی روی برخی آدیپوکاین و هپاتوکاین ها و مقاومت به انسولین در موش های دیابتی نوع یک

الموضوعات : فصلنامه زیست شناسی جانوری

محمد سلماسی 1 , محمد رضا ذولفقاری دیدنی 2 , اکبر نوری حبشی 3

1 - گروه فیزیولوژی ورزشی و حرکات اصلاحی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران
2 - گروه فیزیولوژی ورزشی و حرکات اصلاحی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران
3 - گروه فیزیولوژی ورزشی و حرکات اصلاحی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران

تاريخ الإرسال : 17 الأربعاء , رجب, 1444 تاريخ التأكيد : 05 الإثنين , صفر, 1445 تاريخ الإصدار : 08 الأربعاء , جمادى الأولى, 1445

الکلمات المفتاحية: تمرین هوازی, مقاومت به انسولین, تمرین تناوبی, دیابت نوع 1,

ملخص المقالة :

دیابت به عنوان یکی از بیماری های بسیار توسعه یافته در جهان و از دلایل اصلی مرگ و میر در نظر گرفته می شود. از راه های پیشگیری از دیابت و جلوگیری از عوارض ناشی از آن، انجام فعالیت به روش های مختلف است. هدف از پژوهش حاضر بررسی مقایسه تاثیر دوازده هفته تمرین تداومی و تناوبی روی فتوئین b، فتوئین a و گلیپیکان 4 پلاسما و مقاومت به انسولین در موش های دیابتی نوع 1 بود. برای این منظور 40 موش دیابتی نوع یک به 4 گروه کنترل-سالم، کنترل دیابت، دیابت تمرین تداومی و دیابت تمرین تناوبی تقسیم شدند.گروه تناوبی با دویدن روی در وهله های 3 دقیقه‌ای با سرعت 20 متر در دقیقه و ریکاوری فعال با سرعت 10 متر در دقیقه با شیب صفر درصد به مدت 3 دقیقه روی تردمیل، شش تکرار در هر جلسه انجام شد (مدت زمان کل 36 دقیقه). گروه‌ تمرین تداومی نیز دویدن را با سرعت 15 متر در دقیقه به مدت 36 دقیقه با شیب 0% درصد انجام دادند. کشتار موشها 48 ساعت بعد از آخرین جلسه تمرینی انجام و خونگیری انجام شد. جهت مقایسه بین گروه‌ها از آزمون آنالیز واریانس یک طرفه و آزمون تعقیبی بونفرونی استفاده شد. بررسی تغییرات بین گروهی نشان داد که تفاوت معنی دار بین گروه ها برای مقاومت به انسولین، فتوئین b، فتوئین a و گلیپیکان 4 پلاسما وجود دارد (001/0p <). بررسی تغییرات بین کروهی نشان داد که مقاومت به انسولین، فتوئین b، فتوئین a و گلیپیکان 4 پلاسما کاهش معنی دار در گروه سالم نسبت به گروه دیابتی داشتند (001/0p <). همچنین بین گروه کنترل دیابت با گروه های تمرین تداومی و تمرین تناوبی تفاوت معنی دار بین همه شاخص ها وجود داشت (001/0p <). نتایج پژوهش حاضر نشان داد که تمرین هوازی و تمرین تناوبی میتوانند باعث کاهش فتوئین b، فتوئین a و گلیپیکان 4 پلاسما در موشهای دیابتی نوع 1 شوند. این بهبودها در گروه تمرین تناوبی نسبت به تمرین تداومی بهتر بود.

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