بررسی متابولیت ها و اثرات دارویی گیاه دارویی Salvia rhytidea Benth.
الموضوعات :
1 - بخش بیوشیمی.دانشکده علوم. دانشگاه پیام نور. واحد تهران
الکلمات المفتاحية: دارویی, اثرات, متابولیت, گیاه دارویی,
ملخص المقالة :
گونه های مختلف جنس Salvia از خانواده نعنائیان در طب سنتی به عنوان گیاهان دارویی در مناطق متفاوتی از جهان استفاده می شوند. همین امر باعث شده که پژوهشگران به کاوش در زمینه مواد موثره این گیاهان بپردازند. یکی از گونه های این جنس گیاه Salvia rhytidea Benth.است که از گونه های بومی مناطق شرقی ایران است و در این مناطق به صورت وحشی می روید.این گیاه سابقه استفاده در طب سنتی را داشته و هم اکنون هم به عنوان محرک جریان خون, برطرف کننده لخته خون, پایین اورنده قند خون و انتی اکسیدان استفاده می شود.اخیرا محققان تحقیقاتی را در زمینه کشف متابولیت ها وخواص دارویی این گیاه انجام داده اند . تحقیقات پژوهشگران دراین زمینه تا به امروز حاکی از وجود فلاونوئیدها و تانن ها و ترکیب فنولی رزمارینیک اسید در عصاره متانولی سرشاخه های گلدار و وجود دیترپنوئیدهای متفاوت در عصاره اتری ریشه این گیاه می باشد. از عصاره متانولی سرشاخه های گلدار این گیاه خاصیت ضد قارچی به اثبات رسیده است بعلاوه از عصاره متانولی اندامهای هوایی این گونه شامل سرشاخه های گلدار و برگها و ساقه های جوان خاصیت پایین اورندگی قند خون و خاصیت مهارکنندگی انزیم الفاگلوکزیداز گزارش شده است. قابل ذکر است که خواص دارویی متعددی از جمله خاصیت ضد باکتریایی ,ضد پروتوزوایی, ضد قارچی ,ضد انگل مولد بیماری سالک ,ضد میکروارگانیزمهای مولد بیماری مالاریا و بیماری خواب ,ضد توموری ,ضد سرطانی ,مهارکنندگی انزیمی ,انتی اکسیدانی ,سیتوتوکسیک, پایین اورندگی فشار خون ,انتی کولین استرازی وافت کشی از ریشه این گیاه به اثبات رسیده است.
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