One-pot Synthesis of Polysubstituted Indolizine Derivatives
الموضوعات :
Mohammad Piltan
1
()
Seyed Amir Zarei
2
()
Hassan Saydi
3
()
Ashraf Sadat Shahvelayati
4
()
الکلمات المفتاحية:
ملخص المقالة :
An efficient approach to the synthesis of 1,2,3-trisubstituted indolizines is described via one-pot reactions of pyridine and dialkyl acetylendicarboxylate in the presence of ethyl 2-chloroacetoacetate in MeOH at room temperature. The corresponding 1, 2, 3-trisubstituted indolizines may be useful building blocks for the construction of complex indolizine derivatives.
