reaction of thiohydantoins and ethylbromopyruvate for Synthesis of imidazo[2,1-b]thiazole 3-carboxylate

الموضوعات : International Journal of Heterocyclic Chemistry

Nasimeh Zarei ¹ (Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran,)
Mohammad Mehdi Ghanbari ² (Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran)
Marzieh Jamali ³ (Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran)
Mahboobeh Kiamarsi ⁴ (Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran)
Pegah Mohagheghzadeh ⁵ (Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran)

تاريخ الإرسال : 26 الأربعاء , محرم, 1436 تاريخ التأكيد : 13 السبت , رجب, 1436 تاريخ الإصدار : 12 الأربعاء , جمادى الثانية, 1436

الکلمات المفتاحية: Thiohydantoin, Imidazo[2, 1-b]thiazole, Ethylbromopyruvate, anticancer, Thioxoimidazolidin,

ملخص المقالة :

Imidazo[2,1-b]thiazoles are obtaind in excellent yields from the addition reaction between thiohydantoin and ethylbromopyruvate. These imidazo[2,1-b]thiazoles in the presence of p-TSA in boiling toluene refluxed for 2.5 hours led to imidazo[2,1-b]thiazole-3-carboxylates in elimination reactions

المصادر:

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