New and Efficient Rout for One Pot Synthesis of acenaphtho[1,2-b] quinoxalines
الموضوعات : International Journal of Heterocyclic Chemistry
Zahra Haghighi ju
1
(Department of Medicinal Chemistry , Mazandaran University of Medical Sciences , Sary, Iran)
الکلمات المفتاحية: Synthesis, Acenaphthene-1, 2-dione, pyrimidine , quinoxalines,
ملخص المقالة :
Acenaphtho derivatives have been reported as antitumor agents. So, the reaction of acenaphthylene-1,2-dione with 3,4-diaminobenzenethiol, and then with the alkyl chloride derivatives for the synthesis of acenaphtho [1,2-b] quinoxalines are reviewed. Excellent yields of the products, short reaction times and simple work-up are attractive features of this suitable protocol.
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