Reaction of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol

الموضوعات : International Journal of Heterocyclic Chemistry

Neda Tavakkoli ¹ , Hassan Kabirifard ²

1 - Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran
2 - Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran

تاريخ الإرسال : 14 الإثنين , جمادى الثانية, 1438 تاريخ التأكيد : 16 الجمعة , شعبان, 1438 تاريخ الإصدار : 02 الأربعاء , جمادى الثانية, 1438

الکلمات المفتاحية: Benzoylpyruvate, Aromatic aldehydes, 5-amino-1, 3, 4-thiadizole-2-thiol, Multi-component reactions (MCRs),

ملخص المقالة :

Reactions of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol in a 1:1:1 molar ratio, afforded 5-(5-aryl-4-benzoyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3,4-thiadizole-2-thiols (3a-c). The structure of the resulted products was confirmed by determination of the melting point and spectrophotometric techniques such as IR and 1H-NMR spectroscopy.