Effect of Adagio and Allegro Music on Carrageenan-Induced Inflammation in Male Rats

Subject Areas : Journal of Animal Biology

سیدابراهیم حسینی ¹ (دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه زیست شناسی، فارس، ایران)
فاطمه دلاور اردکانی ² (دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه زیست شناسی، فارس، ایران)
مجید رضا فرخی ³ (دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه زیست شناسی، فارس، ایران)
مختار مختاری ⁴ (دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه زیست شناسی، فارس، ایران)

Received: 2014-06-21 Accepted : 2017-05-21 Published : 2013-04-21

Keywords: Inflammation, Rat, Adagioand Allegro Music, Carrageenan,

Abstract :

Inflammatory is the Negative mode that affected the arachidonic acid metabolites, especially prostaglandin is created. According to side effects of chemical anti-inflammatory drugs, this study was conducted to evaluate the effect of music on the degree of inflammation.In this study, 40 adult male Wistar rats weighing 250-220 g were studied in groups of control, sham and three experimental. The control group was no treated. The sham group wereinjected50 microliters of carrageenan 1% subcutaneouslyand saline intraperitoneally.The experimental group1 wereinjected carrageenansubcutaneously and2mg/kgBW dexamethasone intraperitoneallyand twoothergroupswereinjected carrageenan and adagioand allegro musicrespectively, and based on the formula for measuring the degree of inflammation, extent of inflammation were measured in different groups.The data were evaluated usingANOVA and Tukey.Resultsshowedthat dexamethasone reduces inflammation, while none of the two types of music have an effect on reducing inflammation.Musicthrough reducing function ofthe hypothalamus-pituitary-adrenal axis does not have any effect on inflammation