Protective Effect of Royal Jelly on Methotrexate Infertility in Female Rats

Subject Areas : Journal of Animal Biology

Atikeh Amindoost ¹ , Mona Farhadi ² , Parvin Torabzadeh ³

1 - Department of Biology, Karaj Branch, Islamic Azad University, Karaj, Iran
2 - Department of Biology, Karaj Branch, Islamic Azad University, Karaj, Iran
3 - Department of Biology, Karaj Branch, Islamic Azad University, Karaj, Iran

Received: 2019-09-21 Accepted : 2020-02-04 Published : 2020-02-20

Keywords: royal jelly, Ovary, NMRI mouse, Methotrexate,

References:

1.  Asadi N., Kheradmand A., Gholami M., Saidi S.H., Mirhadi S.A. 2019. Effect of royal jelly on testicular antioxidant enzymes activity, MDA level and spermatogenesis in rat experimental Varicocele model. Tissue and Cell, 57: 70-77.

2.   Asvadi I., Hajipour B., Asvadi A., Asl N., Roshangar L., Khodadadi A. 2011. Protective effect of pentoxyfilline in renal toxicity after methotrexate administration. European Review in Medicine and Pharmacological Sciences, 15(9): 1003-1009.

3.   Ghanbari E., Nejati V., Najafi G., Khazaei M., Babaei M. 2015. Study on the effect of royal jelly on reproductive parameters in streptozotocin-induced diabetic rats. International Journal of Fertility and Sterility, 9(1): 113.

4.  McLaren J.F., Burney R.O., Milki A.A., Westphal L.M., Dahan M.H., Lathi R.B. 2009. Effect of methotrexate exposure on subsequent fertility in women undergoing controlled ovarian stimulation. Fertility and Ssterility, 92(2): 515-519.

5. Najafi G., Nejati V., Shalizar Jalali A., Zahmatkesh E. 2014. Protective role of royal jelly in oxymetholone-induced oxidative injury in mouse testis. Iranian Journal of Toxicology, 8(25): 1073-1080.

6.  Nouri H.S., Azarmi Y., Movahedin M. 2009. Effect of growth hormone on testicular dysfunction induced by methotrexate in rats. Andrologia,1(2): 105-110.

7.  Padmanabhan S., Tripathi D., Vikram A., Ramarao P., Jena G. 2008. Cytotoxic and genotoxic effects of methotrexate in germ cells of male Swiss mice. Mutation Research- Genetic Toxicology and Environmental Mutagenesis, 655(1): 59-67.

8.  Rizk S.M., Zaki H.F., Mina M.A. 2014. Propolis attenuates doxorubicin-induced testicular toxicity in rats. Food and Chemical Toxicology, 67:176-186.

9.    Saxena A., Dhungel S., Bhattacharya S., Jha C., Srivastava A. 2004. Effect of chronic low dose of methotrexate on cellular proliferation during spermatogenesis in rats. Archives of Andrology, 50(1): 33-35.

10.   Sharif S.N., Darsareh F. 2019. Effect of royal jelly on menopausal symptoms: A randomized placebo-controlled clinical trial. Complementary Therapies in Clinical Practice, 37: 47-50.

11.  Sönmez M.F., Çilenk K.T., Karabulut D., Ünalmış S., Deligönül E. 2016. Protective effects of propolis on methotrexate-induced testis injury in rat. Biomedicine and Pharmacotherapy,79: 44-51.

12. Takenaka T. 1982. Chemical composition of royal jelly. Honeybee Science, 3: 69-74.

13.   Yang A., Zhou M., Zhang L., Xie G., Chen H. 2012. Influence of royal jelly on the reproductive function of puberty male rats. Food and Chemical Toxicology, 50(6): 1834-1840.

14.  Zahmatkesh E., Najafi G., Nejati V., Heidari R. 2014. Protective effect of royal jelly on the sperm parameters and testosterone level and lipid peroxidation in adult mice treated with oxymetholone. Avicenna Journal of Phytomedicine, 4(1): 43.

15. Zhao Y., Zheng H.X., Xu Y., Lin N. 2019. Estrogenic Effect of the Extract of QingYan Formula on Reproductive Tissues in Immature Mice. Evidence-Based Complementary and Alternative Medicine. 2019: 5493714.