Determining the frequency distribution of ocular manifestations in multiple sclerosis patients referred MS Society Mashhad

Subject Areas : علوم پزشکی

Ali Al sheykh ¹ , Asana Makhmal Baf ² , Abbas Nourian ³

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Received: 2017-06-05 Accepted : 2017-06-05 Published : 2014-05-22

Keywords: Multiple Sclerosis, ocular manifestations, neurological manifestations,

Abstract :

Introduction: MS is the most common disabling neurological disease in young people. Visual dysfunction is one of the most common clinical manifestation of Multiple Sclerosis. As 25% of people with MS have visual dysfunction. This study aimed to investigate the prevalence of ocular manifestation in MS patients in Mashhad Methods: In this study 150 MS patients from who referred to the MS society Mashhad  were examined. Their ocular and neurological manifestations were recorded in questionnaire. The frequency of these manifestations by age, sex, age of onset, family history and location was assessed. Results: The mean age of patients who were evaluated was 33/48 years. The mean age at onset of the disease was 28/43 years. 126 patients were female and 24 were male. 92% of those were living in urban areas and 16% of patients had a family history of MS. Disc atrophy and optic neuritis with a frequency of 14/7% and 12% were the most common ocular signs in our patients. In 42/7% of patients the onset of disease was only with ocular symptoms. Some ocular manifestations were significantly more common in men, people under 30 years, people living in rural areas and those with family history of MS. 24% of patients had important ocular signs including optic neuritis, disc atrophy, retrobulbar neuritis, papillitis . Conclusion: Visual dysfunction is one of the most common clinical manifestations of MS. The incidence of these manifestations is associated with some factors such as age, sex, age at onset, location and family history. Therefore it is necessary to consider demographic characteristics in the initial evaluation of patient. Ocular symptoms are common at the onset of MS. So in the patients with complaint of ocular symptoms including blurred vision and diplopia MS should be considered.  

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