The Acute Effect of Interval and Continuous Exercises on Levels of Adhesion Molecules in Young Females with Overweight

Subject Areas : Sport Sciences Quarterly

mohsen jafari ¹ (گروه علوم ورزشی، واحد شیروان، دانشگاه آزاد اسلامی، شیروان، ایران)
zahra yekrangi ² (گروه علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران)
mahbobeh marhamati ³ (گروه علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران)
mahsa reyhani ⁴ (گروه علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران)

Received: 1400-11-26 Accepted : 1400-11-26 Published : 1400-09-01

Keywords: Women, Running, interval training, Adhesion Molecules, Selectin,

Abstract :

AbstractAdhesion molecules are mediators of atherosclerotic inflammatory processes. Blood levels of these substances have direct association with cardiovascular disease risk and elevate in heart patients. The aim of this study was to examine the effect of two continuous (cooper test) and interval (RAST test) exercises on levels of ICAM1, VCAM1, E-selectin, P-selectin, and L-selectin. 17 obese and healthy young females were randomly assigned into two groups of Cooper and RAST tests. Blood sampling was done before and after the tests. In statistical analysis, paired T-test was used for interring group comparison and independent T-test was used for between groups comparison. Analysis of data showed that except L-selectin, changes of all dependent variables after cooper and RAST tests were not significant (P>0/05) and only L-selectin levels after cooper test decreased significantly (P≤0/05). Also changes of all of variables between two groups were not significant (P>0/05). overall, one session interval and continuous exercise did not induce elevation of atherogenic adhesion molecules in obese young females that shows protective mechanisms in vascular endothelium in these persons possibly prevents injurious inflammatory response to exercise, thus obese young females can do exercise for weight reduction without anxiety for inflammatory complications induced by exercise trainings.

References:

 

• Akimoto, T., Furudate, M., Saitoh, M., Sugiura, K., Waku, T., Akama, T., & Kono, I. (2002). Increased plasma concentrations of intercellular adhesion molecule-1 after strenuous exercise associated with muscle damage. European journal of applied physiology, 86(3), 185-190.


• Barabadi, A., Ravasi, A. A., Chobineh, S., & Barabadi, H. (2013). The Effect of a Long Prior Aerobic Exercise and High Fat Meal on Inflammatory Markers of Vascular Adhesion Molecule and Lipid Profile in Non–Athlete Males.


• Borges, L., Dermargos, A., Gray, S., Barros Silva, M. B., Santos, V., Pithon-Curi, T. C., ... & Hatanaka, E. (2018). Neutrophil migration and adhesion molecule expression after acute high-intensity street dance exercise. Journal of immunology research, 2018.


• Chadorneshin, H. T., Golestani, A., Jamali, F., Shirvan, S. M. M., Sarir, H., & Eivary, S. H. A. (2018). The response of intercellular adhesion molecule-1 to exhaustive submaximal exercise and its correlation with physiological and anthropometric measures. Journal of medicine and life, 11(1), 36.


• Dustin, M. L. (2019). Integrins and Their Role in Immune Cell Adhesion. Cell, 177(3), 499-501.


• Farsi, S., Azarbayjani, M. A., Hosseini, S. A., & Pirei, P. (2016). Response of Serum Levels of ICAM-1 VCAM-1and CRP to High and Moderate Endurance Trainings in Sprague Dawley Male Diabetic Rats. Armaghane danesh, 21(8), 757-771.


• Glowinska, B., Urban, M., Peczynska, J., & Florys, B. (2005). Soluble adhesion molecules (sICAM-1, sVCAM-1) and selectins (sE selectin, sP selectin, sL selectin) levels in children and adolescents with obesity, hypertension, and diabetes. Metabolism, 54(8), 1020-1026.


• Hou, J., Liu, Y., Xue, X., Wu, Y., Li, R., Xu, T., ... & Zhang, D. (2019). The expression of macrophage migration inhibitory factor and intercellular adhesion molecule-1 in rats with periodontitis and atherosclerosis. Archives of oral biology, 107, 104513.


• Jafari, M. (2018). The Status of Inflammatory Factors Involved in Coronary Artery Disease in Veteran Football Players. Journal of Archives in Military Medicine, 7(3).


• Kupsa, T., Horacek, J. M., & Jebavy, L. (2015). The role of adhesion molecules in acute myeloid leukemia and (hemato) oncology: a systematic review. Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, 159(1).


• Liu, Y., Davidson, B. P., Yue, Q., Belcik, T., Xie, A., Inaba, Y., ... & Kaufmann, B. A. (2013). Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition. Circulation: Cardiovascular Imaging, 6(1), 74-82.


• Mizia-Stec, K., Zahorska-Markiewicz, B., Mandecki, T., Janowska, J., Szulc, A., & Jastrzebska-Maj, E. (2002). Serum levels of selected adhesion molecules in patients with coronary artery disease. International journal of cardiology, 83(2), 143-150.


• Nielsen, H. G., & Lyberg, T. (2004). Long‐Distance Running Modulates the Expression of Leucocyte and Endothelial Adhesion Molecules. Scandinavian journal of immunology, 60(4), 356-362.


• Park, J., Willoughby, D. S., Song, J. J., Leutholtz, B. C., & Koh, Y. (2018). Exercise-induced changes in stress hormones and cell adhesion molecules in obese men. Journal of inflammation research, 11, 69.


• Petridou, A., Chatzinikolaou, A., Fatouros, I., Mastorakos, G., Mitrakou, A., Chandrinou, H., ... & Mougios, V. (2007). Resistance exercise does not affect the serum concentrations of cell adhesion molecules. British journal of sports medicine, 41(2), 76-79.


• Rahmani, H., Ahmadizad, S., Rohani, H., Nouri, H. A., & Mohammadi, D. C. M. (2017). Acute effects of continuous or high intensity interval exercise on plasma levels of e-selectin and wbc indices in chd patients.


• Shephard, R. J. (2003). Adhesion molecules, catecholamines and leucocyte redistribution during and following exercise. Sports medicine, 33(4), 261-284.


• Strömberg, A., Rullman, E., Jansson, E., & Gustafsson, T. (2017). Exercise-induced upregulation of endothelial adhesion molecules in human skeletal muscle and number of circulating cells with remodeling properties. Journal of applied physiology, 122(5), 1145-1154.


• Wang, J. S., Chen, Y. W., Chow, S. E., Ou, H. C., & Sheu, W. H. (2005). Endothelium and Vascular Development-Exercise paradoxically modulates oxidized low-density lipoprotein-induced adhesion molecules expression and trans-endothelial migration of monocyte in men. Thrombosis and Haemostasis, 94(4), 846-852.