The serological identification of subclinical chicken infectious anemia cases and effect of this infection on immune response against avian influenza vaccine (H9N2 subtype) in broiler chickens of Isfahan province

Subject Areas : Journal of Comparative Pathobiology

مجید Gholami-Ahangaran ¹ , نوشا Zia-Jahromi ² , عزت‌اله Fathi ³

1 - ندارد
2 - ندارد
3 - ندارد

Received: 2010-07-08 Accepted : 2010-11-11 Published : 2010-02-20

Keywords: Chicken Infectious Anemia, Influenza, Broiler chicken,

Abstract :

In this study, 375 serum samples were taken from 25 broiler chicken flocks, slaughtered inIsfahan, Iran. Sampling with history recording was done from healthy flocks. Flocks dividedinto 2 groups: vaccinated and nonvaccinated against avian influenza (AI). Sera were tested withCIAV commercial competitive ELISA kit and avian influenza HI titers were determined invaccinated and nonvaccinated flocks. Results shown, the seroprevalence of CIAV in studiedbroiler chicken flocks were 20% to 100% variable and in 375 broiler chickens, without clinicalsigns, were 76.3%. There are no significant differences in seroprevalence of CIAV between AIvaccinated and nonvaccinated flocks. There are no statistical correlation between level of CIAVantibody and AI HI titer, but some low titers were seen in some vaccinated flocks. However, thisstudy shown, there are high seroprevalence of subclinical CIAV in broiler chickens of Isfahanprovince and subclinical infection by this virus could be one cause of immunosuppression andnonproper immune response to vaccines (e.g. AI) in broiler chickens. However, CIAVvaccination of broiler breeder before laying was advised to transmite perfect protectiveimmunity to broiler chickens.