The effect of spirulina supplementation with aerobic exercise on changes in myostatin, follisatin and fat mass in overweight middle-aged people

Subject Areas : New studies in exercise metabolism and physical activity

Seyed amir Kalali ¹ (Department of physical education and sport science, Bojnourd branch, Islamic Azad University, Bojnourd, Iran)

Received: 2022-11-02 Accepted : 2022-12-17 Published : 2023-05-22

Keywords: myostatin, Keywords: aerobic exercise, Follistatin, Spirulina Supplement,

Abstract :

AbstractIntroduction: Overweight and obesity is one of the main problems in today's world that can progress with age and cause various diseases. Therefore, the aim of this study was to investigate the effect of Consumption of the spirulina supplement with aerobic exercise on changes in myostatin, follistatin and fat mass in overweight middle-aged people. Materials and Methods: 35 subjects were randomly divided into three groups: control (n = 11), supplement group (spirulina+aerobic exercise) (n = 12), and placebo (placebo+aerobic exercise) (n = 12). Aerobic exercise was performed with an intensity of 60 to 75% of maximum heart rate for eight weeks with three sessions per week. Also, four grams of spirulina supplement was taken daily. Anthropometric variables, follistatin and myostatin, were measured before and after training. To analyze the data, repeated measures analysis of variance was used and the significance level was considered <0.05. Results: No significant differences were observed between the groups of serum levels of follisatin (p = 0.250), myostatin (p = 0.099) and body fat (p = 0.564). However, intragroup changes showed that body fat was significantly reduced in the supplement and placebo groups (p = 0.001). Conclusion: The use of aerobic exercise and spirulina supplementation, despite not having an effect on follisatin and myostatin, can have a positive effect on the improvement of body composition.Keywords: Aerobic Exercise, Spirulina Supplement, Follistatin, Myostatin