Comparison between epidural injection of calcium–naloxone and intramuscular GnRH as therapeutic methods in the treatment of follicular ovarian cysts in dairy cattle
Subject Areas :
Veterinary Clinical Pathology
amirali kaveh
1
,
saeid Rezaye Haghdoust
2
,
samad mosaferi
3
1 - استادیار گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد تبریز، دانشگاه آزاد اسلامی، تبریز، ایران.
2 - دانش‌آموخته دکتری دامپزشکی، دانشکده دامپزشکی، واحد تبریز، دانشگاه آزاد اسلامی، تبریز، ایران.
3 - استادیار گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد تبریز، دانشگاه آزاد اسلامی، تبریز، ایران.
Received: 2013-10-12
Accepted : 2014-06-24
Published : 2014-08-23
Keywords:
Cow,
Ovarian Cyst,
Gonadorelin,
Calcium-Naloxone,
Abstract :
Ovarian cysts is one of the problems of dairy cattle with high production. The aim of this study was to evaluate the response to treatment of ovarian follicular cysts using calcium naloxone comparison with the conventional method of intramuscular GnRH injection. This study was conducted in third station dairy cattle farming center in Moghan on 54 cows' affected follicular ovarian cysts approximately 100 to 150 days after parturition. Following physical examination and diagnosis of the cystic cows, the animals were divided into three groups. The first group was the control group (5ml GnRH IM), the second group was the treatment group 1 (Nx via epidural injection 2 times with 3 day intervals) and the third group was the treatment group 2 (Ca–Nx via epidural injection 2 times with 3 day intervals and 5 ml of intramuscular GnRH simultaneously with the second Ca-Nx injection). To check the results, the animals was examined two weeks after the last injection. The results indicated that there was a significant difference in luteinization rate between the first and second groups with more luteinization rate in the first group. There was no significant difference between the first and third group in luteinization rate. Also, there was a significant difference in luteinization rate between the second and third group, with more luteinization rate observed in the third group. There was no significant difference between the fertility rate of the treatment and control groups.
References:
· Arthur, G.H., Noakes, D.E. and Parkinson, T.J. (2001). Veterinary Reproduction and Obstetrics. 7rd ed., UK: Bailliere Tindull, pp: 430-442.
· Currie, W.S. and Rawlings, N.C. (1989). Fluctutation in responsiveness of LH and lack of responsiveness of FSH to prolonged infusions of morphine and naloxone in the ewe. Journal of Reproduction and Fertility, 8(6): 359-366.
· De Vries, A., Crane, M.B. Bartolome, J.A., Melendez, P., Risco, C.A. and Archibald, L.F. (2006). Economic comparison of timed artificial insemination and exogenous progesterone as treatments for ovarian cysts. Journal of Dairy Science, 89(3): 3028- 3037.
· Duffy, P., Crowe, M.A. Boland, M.P. and Roche, J.F. (2000). Effect of exogenous LH pulses on the fate of the first dominant follicle in postpartum beef cows nursing calves. Journal of Reproduction and Fertility, 11(8): 9-17.
· Ebling, J.P. and Lincoln, G. (1985). Endogenous opioids and the control of seasonal LH secretion in Soay Rams. Journal of Endocrinology, 107:341-353.
· Fuentes, V.O., Bernal, A. and Fuentes, P.I., (2009). A comparative study using an opioid antagonist and GnRH for the treatment of follicular cysts in dairy Holstein cows. Journal of Biological Sciences, 9 (8): 833-836.
· Fuentes, V.O., Gonzalez, H., Sanchez, V.M. and. Fuentes, P.I. (2007). Effect of small doses of naloxone on the pulsatile secretion of prolactin in the crossbreed ewe during the non-breeding season. Animal Reproduction Sciences, 100: 44-50.
· Horton, J.E. and Clarke, I.J. (1988). Lack of effect of morphine or naloxone on the estrogen-induced LH surg in anoestrous ewes. Journal of Endocrinology, 119: 89-93.
· Katz, N. and Mazer, N.A. (2009). The impact of opioids on the endocrine system. Clinical Journal of Pain, 25: 170-175.
· Noakes, D.E., Parkinson T.J. and England G.W. (2009). Veterinary Reproduction and Obstetrics. 9rd ed., UK: Bailliere Tindull, pp: 565-576.
· Savio, J.D., Boland, M.P., Hynes, N. and Roche, J.F. (1990). Resumption of in the early post-partum period of dairy cow. Journal of Reproduction and Fertility, 88: 569-579.
· Sciorsci, R.L., Robbe, D., Di matteo, A., La calandra, G.M. and Minoia, P. (2000). The treatment of ovarian Follicular cystis in dairy cows with epidural calcium-naloxone and systemic GnRH administration: a preliminary field study. 14th International Congress of Animal Reproduction, Stockholm, Sweden, 12: 7, 13.
· Stagg, K., Spicer, L.J., Sreemen, J.M., Roche, J.F. and Diskin, M.G. (1998). Effect of calf isolation on folicular wave dynamics, gonadotropin and metabolic hormone changes and interval to first ovulation in beef cows fed either of tow energy levels postpartum. Biology and Reproduction, 59: 777-783.
· Wojcikladyz, A., Nowak, K.W., Pierzchala-koziec, K., Wankowska, M. and Misztal, T. (2006). Aspects of central and peripheral regulation of reproduction in mammals. Biolgy and Reproduction, 71: 89-103.
· Yang, K., Haynes, N.B., Lamming, G.E. and Brooks, A.N. (1988). Ovarian steroid involvement in endogenous opioid modulation of LH secretion in mature ewes during the breeding and non breeding seasons. Journal of Reproduction and Fertility, 8(3): 129-139.
