Serumic concentration of cardiac troponin and some enzymes in horses with strangles

Subject Areas : Veterinary Clinical Pathology

علی Hassanpour ¹ (Assosiate Professor, Department of Clinical Science, Faculty of Veterinary Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran)
مجید Fartashvand ² (Assistant Professor, Department of Clinical Science, Faculty of Veterinary Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran)

Received: 2012-11-02 Accepted : 2013-01-30 Published : 2013-02-19

Keywords: horse, : Strangles, Cardiac troponin. Serum enzymes,

Abstract :

This study was conducted on horses to investigate the effect of strangles on cardiac troponin fluctuations and activity of some serum enzymes. The research was done on 30 horses with strangles and 29 normal horses. Sick horses were confirmed on the basis of clinical and laboratory signs (culture of nasal and lymph nodes discharges for Streptococcus equi). Blood samples were taken from the jugular vein. The serum activity of cardiac troponin was measured by ELISA kit and gama gluthamil transferase (GGT), alanine amino tramsferase (ALT), aspartate amino transferase (AST), creatine kinase (CK) and alkaline phosphatase (ALP) were measured by biochemical kits. The mean heart rate increased significantly (p<0.05) in horses with strangles. The mean cardiac troponin also increased significantly (p=0.001). Serum activity of GGT, CK, ALP and ALT enzymes were increased significantly (p= 0.41, p= 0.006 and p=0.001, respectively) in horses with strangles. In conclusion, serumic concentration of cardiac troponin and GGT, CK, ALP and ALT enzymes increase after strangles in the horse.

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