Mapping of QTLs Controlling Egg Quality on Chromosomes 6-8, Z and Three Linkage Groups in Chickens
محورهای موضوعی : CamelS.J. Rosochacki 1 , R. Olszewski 2 , B. Wardecka 3 , K. Jaszczak 4 , G. Zieba 5 , E. Juszczuk-Kubiak 6 , J. Poloszynowicz 7
1 - Institute of Genetics and Animal Breeding, PAS, Jastrzębiec, 05-552, Magdalenka, Poland
Bialystok Technical University, 15-351, Bialystok, Poland
2 - Institute of Genetics and Animal Breeding, PAS, Jastrzębiec, 05-552, Magdalenka, Poland
3 - Institute of Genetics and Animal Breeding, PAS, Jastrzębiec, 05-552, Magdalenka, Poland
4 - Institute of Genetics and Animal Breeding, PAS, Jastrzębiec, 05-552, Magdalenka, Poland
5 - Agriculture Academy, 20-950, Lublin, Poland
6 - Institute of Genetics and Animal Breeding, PAS, Jastrzębiec, 05-552, Magdalenka, Poland
7 - Institute of Genetics and Animal Breeding, PAS, Jastrzębiec, 05-552, Magdalenka, Poland
کلید واژه: microsatellites, egg quality traits, chickens, QTL mapping,
چکیده مقاله :
Two breeds of chickens were used to develop reference family and detect QTLs affecting egg quality traits: cocks of a native Polish breed Green-Legged Partidgenous (GlP) and hens of Rhode Island Red (RIR). During the first 100 days of the laying period, the GlP hens lay about 40 eggs weighting on average 50 g, whilst the RIR flock laid 83 eggs with a mean weight of 60 g. QTL analysis of egg quality traits was performed on 552 birds of the F2 generation with the aid of 19 microsatellite loci on chromosomes 6, 7, 8, Z and linkage groups 9 (E 36), 19 (E 52) and 26 (E 46). Linkage analysis was performed for 19 microsatellite markers within the mapped population and ten QTLs were found to affect seven egg quality traits: at week 53-shell thickness, shell strength, albumen weight, egg specific gravity and percent of yolk in egg; and at week 33-percent of yolk in egg and Hugh’s units.
Abasht B., Dekkers J.C.M. and Lamont S.J. (2006). Review of quantitative trait loci identified in the chicken. Poult. Sci. 85, 2079-2096.
Abasht B., Sandford E., Arango J., Settar P., Fulton J.E., O’Sullivan N.P., Hassen A., Habier D., Fernando R., Dekkers J.C.M. and Lamont S.J. (2009). Extent and consistency of linkage disequilibrium and identification of DNA markers for production and egg quality traits in commercial layer chicken populations. GBMC. Genomics. 10, 23-27.
Basten C.J., Weir B.S. and Zeng Z.B. (1999). Cartographer ver. 1.13.
Bumsted N. and Palyga J. (1992). A preliminary linkage map for the chicken genome. Genomics. 13, 690-697.
Cheng H.H., Levin I., Vallejo R.L., Khatib H., Dodgson J.B., Crittenden L.B. and Hillel J. (1995). Development of a genetic map of the chicken with markers of high utility. Poult. Sci. 74, 1855-1874.
Churchill G.A. and Doerge R.W. (1994). Empirical threshold values for quantitative trait mapping. Genetics. 138, 963-971.
Crittenden L.B., Provencher L., Santangello L., Levin I., Abolanalp H., Briles R.W., Briles W.E. and Dogson J.B. (1993). Characterization of a Red Jungle Fowl by White Leghorn backcross reference population for molecular mapping of the chicken genome. Poult. Sci. 72, 334-348.
Burt D.W. (1996). Development of genetic map of the chicken withSmarkersSofShighSutility. htt:www.thearkdb.org/browser?objtype=reference&objopr=retrieve&species=chicken&ref_uid=163
Crooijmans R.P.M.A., Groen A.F., Van Kampen A.J.A., Van Der Beek S., Van Der Poel J.J. and Groenen M.A.M. (1996a). Microsatellite polymorphism in commercial broiler and layer lines estimated using polled blood samples. Poult. Sci. 75, 904-909.
Crooijmans R.P.M.A., Van Oers P.A.M., Strijk J.A., Van Der Poel J.J. and Groenen M.A.M. (1996b). Preliminary linkage map of the chicken (Gallus domesticus) genome based on microsatellite markers: 77 new markers mapped. Poult. Sci. 75, 746-754.
Crooijmans R.P.M.A., Dijkhof R.J.M., Groen A.F., Van Der Poel J.J. and Groenen M.A.M. (1997). New microsatellite markers in chicken optimized for automated fluorescent genotyping. Anim. Genet. 28, 427-437.
Diez-Tascon C., Bayon Y., Arranz J.J., De La FuenteF. and San Primitivo F. (2001). Mapping quantitative trait loci for milk production traits on bovine chromosome 6. J. Dairy Res. 68, 389-397.
Fadiel A., AnidI I. and Eichenbaum K.D. (2005). Farm animal genomics and informatics: an update. Nucl. Acid. Res. 33, 6308-6318.
Gelderman H., Moser G., Muller E., Beechmann P., Yue G., Dragos M., Bartenschlager H., Cepita S., Stratil A. and Schroffel J. (1999). Status of genome and QTL mapping in pigs-data on Hohenhein F2 families. Arch. Anim. Breed. 42, 67-81.
Gibbs M., Dawson D.A., Mc Camly C., Wardle A.F., Armour J.A.L. and Burke T. (1997). Chicken microsatellite markers isolated from libraries enriched for simple tandem repeats. Anim. Genet. 28, 401-417.
Green P., Falls K. and Crooks S. (1990). Documentation for CRI-MAP Version 2.4 (3/26/90).
Grobet L., Martin L.J., Poncelet D., Pirottin D., Brouwers B., Riquet J., Schoeberlein A., Dunner S., Meuissier F., Massabanda J., Fries R., Hanset R. and Georges M. (1997). A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat. Genet. 17, 4-5.
Groenen M.A.M., Crooijmans R.P.M.A., Veenendall A., Cheng H.H., Siwek M. and Van Der Poel J.J. (1998). A comprehensive microsatellite linkage map of the chicken genome. Genomics. 49, 265-274.
Groenen M.A.M., Crooijmans R.P.M.A., Veenendall A., Van Kaam J.B.C.H.M., Vereijken A.L.J., Van Arendonk J.A.M. and Van Der Poel J.J. (1997). QTL mapping in chicken using a three generation full sib family structure of an extreme broiler x broiler cross. Anim. Biotechnol. 8, 41-46.
Hansen C., YI N., Zhang Y.M., Xu S., Gavora J. and Cheng H.H. (2005). Identification of QTL for production traits in chickens. Anim. Biotechnol. 16, 67-79.
Hillel J. (1997). Map-based quantitative trait locus identification. Poult. Sci. 76, 1115-1120.
Honkatukia M., Tiskula-Haavisto M., Vilkki J., De Koning D.J., Schulman N. and Maki-Tanila A. (1999). Mapping of quantitative trait loci affecting egg quality in chicken. Pp. 22-26 in Proc. 50th Ann. Meet. Europ. Asso. Anim. Prod. Switzerland.
Jaszczak K., Wardęcka B., Olszewski R., Zięba G. and Pierzchała M. (2001). A new reference family (Green-Legged Partidgenous × Rohde Island Red) for mapping QTLs In laying hens. Anim. Sci. Pap. Rep. 19,131-139.
Korstanje R. and Paigen B. (2002). From QTL to gene: The harvest begins. Nat. Genet. 31, 235-236.
Kuhnlein U., Ni L., Weigend S., Gavora J.S., Fairfull W. and Zadworny D. (1997). DNA polymorphism in the chicken growth hormone gene: response to selection for disease resistance and association with egg production. Anim. Genet. 28, 116-123.
Lander E.S. and Kruglyak L. (1995). Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet. 11,241-247.
Lynch M. and Walsh B. (1998). Genetics and Analysis of Quantitative Traits. Sinauer Associates. Inc. Sauderland, USA.
Malek M., Dekkers J.C., Lee H.K., Baas T.J., Prusa K., Huff-Lonergan E. and Rothschild M.F. (2001). A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. II. Meat and muscle composition. Mam. Genome. 12, 637-645.
Montgomery G.W., Crawford A.M., Penty J.M., Dodds K.G., Ede A.J., Henry H.M., Pierson C.A., Lord E.A., Galloway S.M. and Schmack A.E. (1993). The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 4 q. Nat. Genet. 4,327-328.
Nei M. (1978). Estimation of average heterozygosity and genetic distance from a small number of individuals. Genetics. 89, 583-590.
Paterson H. (1995). Molecular dissection of quantitative traits; progress and prospects. Genome. Res.5,321-333.
Reynolds J., Weir B.S. and Cockerham C.C. (1983). Estimation of the co-ancestry coefficient: basis for short-time genetic distance. Genetics. 105,767-779.
Rosochacki S.J., Hillel J., Jaszczak K. and Zawadzka M. (1997). DNA fingerprinting generated by R.18.1 DNA probe in two stocks of chickens: Green Legged Patrigenous (GLP) and Rohde Island Red (RIR). J. Appl. Genet. 38, 173-178.
Ruyter-Spira C.P., Crooijmans R.P.M.A., Dijkhof R.J.M., Van Oers P.A.M., Strijk J.A., Van Der Poel J.J. and Groenen M.A.M. (1996). Dewelopment and mapping of polymorphic microsatellite markers derived from a chicken brain cDNA library. Anim. Genet. 27, 229-234.
Sasaki O., Odawara S., Takahashi H., Nirasawa K., Oyamada Y., Yamamoto R., Ishii K., Nagamine Y., Takeda H., Kobayashi E. and Furukawa T. (2004). Genetic mapping of quantitative trait loci affecting body weight, egg character and egg production in F2 intercross chickens. Anim. Genet. 35,188-194.
Schreiweis M.A., Haster P.Y., Settar P. and Moody D.E. (2005). Identification of quantitative trait loci associated with egg quality, egg production, and body weight in an F2 resource population of chickens. Anim. Gen. 37,106-112.
Sewalem A., Morice D.M., Law A., Windsor D., Haley C.S., Ikeobi C.O.N., Burt D.W. and Hocking P.M. (2002). Mapping of quantitative trait loci for body weight at three, six and nine weeks of age in a broiler layer cross. Poult. Sci. 81, 1775-1781.
Siwek M., Cornelissen S.J.B., Buitenhuis A.J., Nieuwland M.G.B., Bovenhuis H., Croojmans R.P.M.A., Groenen M.A.M., Parmentier H.K. and Van Der Poel J.J. (2004). Quantitative trait loci for body weight in layers differ from quantitative trait loci specific for antibody responses to sheep red blood cells.Poult. Sci. 83, 853-859.
Soller M. (1991). Mapping quantitative traits loci affecting traits of economic importance in animal populations using molecular markers. In Gene Mapping: Strategies, Techniques and Applications. L.B. Schook, H.A. Lewin and A.G. Mc LarenEds. Marcel Dekker. New Yourk. USA.
Tatsuda K. and Fujinaka K. (2001). Genetic mapping of QTL affecting body weight in chickens using a F2 family. Br. Poutl. Sci. 42, 333-337.
Tuiskula-Haavisto M., Honkatukia M., Vilkki J., De Koning D.J., Schulman N. and Maki-Tanila A. (1999). QTL-mapping for egg quality and production in egg-layers. Pp. 6-8 in Proc. Poult. Genet. Sympo, Germany.
Tuiskula-Haavisto M., Honkatukia M., Vilkki J., De Koning D.J., Schulman N. and Maki-Tanila A. (2002). Mapping of quantitative trait loci affecting quality and production traits in egg-layers. Poult. Sci. 81, 919-927.
Vallejo R.L., Bacon L.D., Liu H.C., Witter R.L., Groenen M.A.M., Hillel J. and Cheng H.H. (1998). Genetic mapping of quantitative trait loci affecting susceptibility to Marek’s disease virus induced tumours in F2 inter-cross chickens. Genetics. 148, 349-360.
Vanhala T., Tuiskula-Haavisto M., Elo K., Vilkki J. and Maki-Tanila A. (1998). Evolution of genetic variability and genetic distance between eight chicken lines using microsatellite markers. Poult. Sci. 77,783-790.
Van Kaam J.B.C.H.M., Groenen M.A.M., Bovenhuis H., Veenendall A., Vereijken A.L.J. and Van Arendok J.A.M. (1999a). Whole genome scan in chickens for quantitative trait loci affecting growth and feed efficiency. Poult. Sci. 78, 15-23.
Van Kaam J.B.C.H.M., Groenen M.A.M., Bovenhuis H., Veenendall A., Vereijken A.L.J. and Van Arendok J.A.M. (1999b). Whole genome scan in chickens for quantitative trait loci affecting carcass traits. Poult. Sci. 78, 1091-1099.
Van Kaam J.B.C.H.M., Van Arendok J.A.M., Groenen M.A.M., Bovenhuis H., Vereijken A.L.J., Crooijmans R.P.M.A., Van Der Poel J.J. and Veenendall A. (1998). Whole genome scan in chickens for quantitative trait loci affecting body weight in chickens using a three generation design. Lives. Prod. Sci. 54, 133-150.
Wardęcka B., Olszewski R., Jaszczak K., Zięba G., Pierzchała M. and Wicińska K. (2002). Relationship between microsatellite marker alleles on chromosomes 1-5 originating from the Rhode Island Red and Green-Legged Partrigenous breeds and egg production and quality traits in F2 mapping population. J. Appl. Genet. 43, 319-329.
Wardęcka B., Olszewski R., Jaszczak K., Zięba G. and Pierzchała M. (2003). Preliminary mapping of QTLs affecting egg quality on chromosomes 1-5 inchickens. Czech J. Anim. Sci. 48, 97-105.
Wright D., Kerje S., Lundstrom K., Babol J., Schutz K., Jensen P. and Andersson L. (2006). Quantitative trait loci analysis of egg and meat production traits in red jungle fowl x White Leghorn cross. Anim. Genet. 37, 529-534.
Yonash N., Cheng H.H., Hillel J., Heller D.E. and Cahaner A. (2001). DNA microsatellites linked to quantitative trait loci affecting antibody response and survival rate in meat-type chickens. Poult. Sci. 80, 22-28.
Yonash N., Bacon L.D., Witter R.L. and Cheng H.H. (1999). High
resolution mapping and identification of new quantitative trait loci (QTL) affecting susceptibility to Marek’s disease. Anim. Genet. 30, 126-135.
Zeng Z.B. (1993). Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci. Proc. Nat. Acad. Sic. USA. 90, 10972-10976.
Zeng Z.B. (1994). Precision mapping of quantitative trait loci. Ge-netics. 136, 1457-1468.
Zhi-Liang H.U., Park C.A., Fritz E.R. and Reecy J.M. (2010). QTLdb: a comprehensive database tool building bridges between genotypes and phenotypes. 9th World Cong. Genet. Appl. Livest. Prod. Leipzig, Germany.
Zhou H. and Lamont S.J. (1999). Genetic characterization of biodiversity in highly inbred chicken lines by microsatellite markers. Anim. Genet. 30, 256-264.
Zhu J.J., Lillehoj H.S., Cheng H.H., Pollock D., Sadjadi M. and Emara M.G. (2001). Screening for highly heterozygous chickens in outbreed commercial broiler lines to increase detection power for mapping quantitative trait loci. Poult. Sci. 80, 6-12.
