Estrogens Receptors-New Players in Spermatogenesis
محورهای موضوعی : Camel
س. سارازوات
1
(Department of Physiology Reproduction and Shelter Management, Central Institute for Research on Goats, Mathura, India)
کلید واژه: estrogen, Testis, aromatase, estrogen receptors,
چکیده مقاله :
The mammalian testis is a complex organ that serves two important functions, synthesis of steroids, with significant amount of estrogenic hormones produced and production of spermatozoa. Estrogen receptors (ERs) are expressed in cells of the testis as well as the epididymal epithelium. We have demonstrated that estrogen receptor expression is higher in reproductive tissues as compared to non-reproductive tissues. In addition to this, western blot analysis showed a signal for estrogen receptor.
بیضه پستانداران یک عضو پیچیده است که دو نقش مهم بر عهده دارد: تولید استروییدها (تولید حجم بالای هورمونهای استروژنیک) و تولید اسپرم. گیرندههای استروژن (ER) در سلولهای بیضه و سلولهای اپیتلیوم بافت اپیدیدیم بیان میشوند. در این مقاله نشان داده شده است که بیان گیرندههای استروژن در بافتهای تولیدمثلی در مقایسه با بافتهای دیگر بیشتر است. علاوه بر این، آنالیزهای لکهگذاری وسترن نشان دهنده یک سیگنال برای گیرنده استروژن است.
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