Mitochondrial Diversity and Phylogenetic Structure of Marghoz Goat Population
محورهای موضوعی : Camel
ح.ر. سیدآبادی
1
(Department of Animal Biotechnology, Animal Science Research Institute, Karaj, Iran)
ک. پهلوان افشاری
2
(Department of Animal Science, Abhar Branch, Islamic Azad University, Abhar, Iran)
م. عبدالمالکی
3
(Department of Animal Science, Abhar Branch, Islamic Azad University, Abhar, Iran)
کلید واژه: genetic diversity, Marghoz goat, mtDNA, phylogenetic,
چکیده مقاله :
The genetic diversity and phylogenetic structure was analyzed in Marghoz goat population by mitochondrial DNA sequences. Phylogenetic analysis was carried out using hyper variable region 1 (968 bp) obtained form 40 animals. Marghoz goat proved to be extremely diverse (average haplotype diversity of 0.999) and the nucleotide diversity values 0.022. A total of 40 Marghoz goats were grouped into six haplotypes and the large majority of haplotypes were present in 15 animals. All Marghoz haplotypes were classified into C haplogroup and revealed remarkably high genetic distances within the population when compared with other Asian goat populations, indicating high genetic variation in the Marghoz goat. These results indicate high-divergence status of the Marghoz goat and will influence breeding and conservation strategies adopted for this breed.
تنوع میتوکندری و ساختار فیلوژنتیکی جمعیت بز مرخز بر اساس توالی DNA میتوکندریایی مورد بررسی قرار گرفت. آنالیز فیلوژنتیکی بر اساس توالی ناحیه HVR1 ( 968 جفت باز) و بر روی 40 رأس بز مرخز انجام گرفت. نتایج نشان داد که جمعیت بز مرخز دارای تنوع ژنتیکی بسیار بالا ( میانگین تنوع هاپلوتیپی 999/0 و تنوع نوکلئوتیدی 022/0) میباشد. در بین 40 نمونه، 6 هاپلوتیپ مشاهده شد و بزرگترین هاپلوتیپ شامل 15 فرد بود. تمام هاپلوتیپها در هاپلوگروپ C و با فاصله ژنتیکی زیاد از سایر جمعیتهای بز آسیایی قرار گرفتند که این بیانگر تنوع ژنتیکی زیاد بز مرخز میباشد. تنوع ژنتیکی بالای مشاهده شده، در اصلاح نژاد و تعیین استراتژیهای حفاظت بز مرخز میتواند مؤثر باشد.
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