Synergistic Effects of Sub-Lethal Concentrations of Deltamethrin on Lead Acetate Toxicity in Japanese Quail (Coturnix japonica)

محورهای موضوعی :

Fatemeh Hamidipoor ¹ , Mahdi Banaee ² , Hamid Reza Pourkhabbaz ³ , Saeideh Javanmardi ⁴

1 - Department of Environment, Faculty of Natural Resources and Environment, Behbahan Khatam Al-anbia University of Technology, Behbahan, Iran
2 - Department of Fisheries and Aquaculture, Faculty of Natural Resources and Environment, Behbahan Khatam Al-anbia University of Technology, Behbahan, Iran
3 - Department of Environment, Faculty of Natural Resources and Environment, Behbahan Khatam Al-anbia University of Technology, Behbahan, Iran
4 - Department of Environment, Faculty of Natural Resources and Environment, Behbahan Khatam Al-anbia University of Technology, Behbahan, Iran

تاریخ دریافت : 1394/11/07 تاریخ پذیرش : 1397/08/07 تاریخ انتشار : 1397/08/07

کلید واژه: Japanese quail, Blood biochemical parameters, deltamethrin, Lead acetate,

چکیده مقاله :

The purpose of this study was to investigate the hypothesis weather the combination of lead acetate and deltamethrin can enhance avian toxic effects produced by lead exposure only. Overall, 48 Japanese quails, Coturnix coturnix Japonica (15 day old) were randomly divided into 4 experimental groups of 12 birds each and sex ratio of 1:1. Experimental groups consisted of control Japanese quails, birds exposed to a single dose of lead acetate and lead acetate combined with sub-lethal doses of deltamethrin (0.25 and 0.50 mg. kg-1 diet) for 21 days. We studied the effects of a single dose of lead acetate, combined with deltamethrin, on survival and blood biochemical parameters of Japanese quails. The results revealed a signiï‌cant increase in plasma AST and ALT activities, glucose, uric acid and creatinine levels after feeding quails with contaminated diet (P <0.05). There was a significant increase in CPK and LDH activities and triglyceride levels in the blood of quails fed diets contaminated with a combination of lead acetate and deltamethrin (P <0.05). The decrease in AChE and ALP activities, total protein, and globulin was observed in plasma of quails fed contaminated diets. There were no significant changes in albumin levels. Although oral administration of lead acetate combined with 0.25 mg deltamethrin caused a significant increase in cholesterol levels, no significant differences were observed in triglyceride levels in other treatments. The synergic effects of deltamethrin on the alterations in the blood biochemical parameters of quails exposed to lead highly depend on the concentrations of this pesticide in feedstuffs.

منابع و مأخذ:

1. Banaee M., Beitsayah A., Jorabdoz I., 2015. Assessment of mercury bioaccumulation in zebra cichlid (Cichlasoma nigrofasciatum) exposed to sub-lethal concentrations of permethrin. Iran J Toxicol. 8(27), 1168-1173.
2. Banaee M., Mohammadipour S., Madhani S., 2015. Effects of sub-lethal concentrations of permethrin on bioaccumulation of cadmium in zebra cichlid (Cichlasoma nigrofasciatum). Toxicol Environ Chem. 97(2), 200-207.
3. Pain D.J., Fisher I.J., Thomas V.G., 2009. A global update of lead poisoning in terrestrial birds from ammunition sources. In Ingestion of Lead from Spent Ammunition: Implications for Wildlife and Humans; The Peregrine Fund, Boise, Idaho, USA. 99-118.
4. Coeurdassier M., Fritsch C., Faivre B., Crini N., Scheifler R., 2012. Partitioning of Cd and Pb in the blood of European blackbirds (Turdus merula) from a smelter contaminated site and use for biomonitoring. Chemosphere. 87, 1368ââ‚‌“1373.
5. Bampidis V.A., Nistor E., Nitas D., 2013. Arsenic, cadmium, lead and mercury as undesirable substances in animal feeds. Animal Sci Biotechnol. 46(1), 17-22.
6. Kertész V., Bakonyi G., Farkas B., 2006. Water pollution by Cu and Pb can adversely affect mallard embryonic development. Ecotoxicol Environ Saf. 65(1), 67-73.
7. Kertész V., Fáncsi F., 2003. Adverse effects of (sur-face water pollutants) Cd, Cr and Pb on the embryogenesis of the mallard. Aquatic Toxicol. 65(4), 425-433.
8. Ninomiya R., Koizumi N., Murata K., 2004. Metal concentrations in the liver and kidney of aquatic mammals and penguins. Biol Trace Element Res. 97(2), 135-148.
9. Baos R., Blas J., Bortolotti G.R., Marchant T.A., Hiraldo F., 2006. Adrenocortical response to stress and thyroid hormone status in free-living nestling white storks (Ciconia ciconia) exposed to heavy metal and arsenic contamination. Environ Health Perspective. 114(10), 1497-1501.
10. Kerr R., Holladay J., Holladay S., Tannenbaum L., Selcer B., Meldrum B., Williams S., Jarrett T., Gogal R., 2011. Oral lead bullet fragment exposure in northern bobwhite (Colinus virginianus). Arch Environ Contam Toxicol. 61(4), 668-376.
11. Mateo R., Taggart M., Meharg A.A., 2003. Lead and arsenic in bones of birds of prey from Spain. Environ Pollution. 126(1), 107-114.
12. Baos R., Jovani R., Forero M.G., Tella J.L., Gómez G., Jiménez B., González M.J., Hiraldo F., 2006. Relationships between T-cell-mediated immune response and Pb, Zn, Cu, Cd, and as concentrations in blood of nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from Doñana (southwestern Spain) after the Aznalcóllar toxic spill. Environ Toxicol Chem. 25(4), 1153-1159.
13. Mora M.A., 2003. Heavy metals and metalloids in egg contents and eggshells of passerine birds from Arizona. Environ Pollution. 125(3), 393-400.
14. Martinez-Haro M., Green A.J., Mateo R., 2011. Effects of lead exposure on oxidative stress biomarkers and plasma biochemistry in waterbirds in the field. Environ Res. 111(4), 530-538.
15. Fields P.G., 2006. Alternatives to chemical control of stored-product insects in temperate regions. The Ninth International Working Conference of Stored Product Protection, Campinas, Brazil. Pp. 653-662.
16. Kljajić P., Perić I., 2009. Residual effects of del-tamethrin and malathion on different populations of Sitophilus granarius (L.) on treated wheat grains. J Stored Products Res. 45(1), 45-48.
17. Tariq M., Bushra S., Mansoor-ul-Hassan U., Maqbool M.R., Asi A., Gulzar A., Iqbal M.F., 2014. Residual estimation of soproturon, atrazine and grain protectants in stored wheat grains. Int J Comput Biol Inform Control. 1(1), 9-25.
18. Savi G.D., Piacentini K.C., Scussel V.M., 2015. Reduction in residues of deltamethrin and fenitrothion on stored wheat grains by ozone gas. J Stored Products Res. 61, 65-69.
19. Cognard C., 2010. Deltamethrin residues through the food chain industries. 10th International working Conference on Stored Product Protection, Estoril, Portugal. Julius Kühn-Institut, Berlin, Germany. Pp 825-826.
20. Hamidipoor F., Pourkhabbaz H.R., Banaee M., Javanmardi S., 2015. Sub-lethal toxic effects of deltamethrin on blood biochemical parameters of Japanese quail, Coturnix japonica. Toxicological & Environmental Chemistry. Article in press.
21. Reddy G.R., Basha M.R., Devi C.B., Suresh A., Baker J.L., Shafeek A., Heinz J., Chetty C.S., 2003. Lead induced effects on acetylcholinesterase activity in cerebellum and hippocampus of developing rat. Int J Develop Neuro. 21(6), 347-352.
22. Banaee M., Sureda A., MirvagheïÂ‌ A.R., Ahmadi K., 2011. Effects of diazinon on biochemical parameters of blood in rainbow trout (Oncorhynchus mykiss). Pesticide Biochem Physiol. 99, 1ââ‚‌“6.
23. Richetti S.K., Rosemberg D.B., Ventura-Lima J., Monserrat J.M., Bogo M.R., Bonan C.D., 2011. Acetylcholinesterase activity and antioxidant capacity of zebrafish brain is altered by heavy metal exposure. Neuro Toxicol. 32(1), 116-122.
24. Yousef M.I., Awad T.I., Mohamed E.H., 2006. Deltamethrin-induced oxidative damage and biochemical alterations in rat and its attenuation by vitamin E. Toxicology. 227, 240-247.
25. Banaee M., 2013. Physiological dysfunction in fish after insecticides exposure. In Insecticides often Undesired but still so Important; InTech: Rijeka, Croatia. Pp. 103-142.
26. Farah H.S., Al-Atoom A.A., Shehab G.M., 2012. Explanation of the decrease in alkaline phosphatase (ALP) activity in hemolysed blood samples from the clinical point of view: In vitro study. Jordan J Biol Sci. 5(2), 125-128.
27. Eraslan G., Bilgili A., Essiz D., Akdogan M., Sahindokuyucu F., 2007. The effects of deltamethrin on some serum biochemical parameters in mice. Pesticide Biochem Physiol. 87, 123ââ‚‌“130.
28. Banaee M., 2012. Adverse effects of insecticides on various aspects of fishââ‚‌™s biology and physiology. In Insecticides - Basic and Other Applications; InTech: Rijeka, Croatia. Pp. 101-128.
29. Hussain R., Khan A., Mahmood F., Rehan S., Ali F., 2014. Clinico-hematological and tissue changes induced by butachlor in male Japanese quail (Coturnix japonica). Pesticide Biochem Physiol. 109, 58ââ‚‌“63.
30. Hussain R., Mahmood F., Khan A., Javed M.T., Rehan S., Mehdi T., 2012. Cellular and biochemical effects induced by atrazine on blood of male Japanese quail (Coturnix Japonica). Pesticide Biochem Physiol. 103, 38-42.
31. Hussain R., Khan A., Mahmood F., 2013. Pathological and some serum biochemical effects induced by malathion in Japanese quail (Coturnix japonica). J Anim Plant Sci. 23, 1501-1506.
32. Bálint T., Szegletes T., Szegletes Z., Halasy K., Nemcsók J., 1995. Biochemical and subcellular changes in carp exposed to the organophosphorus methidathion and the pyrethroid deltamethrin. Aqua Toxicol. 33(4), 279-295.
33. Banaee M., Nematdoust Haghi B., Ibrahim A.T.A., 2013. Sub-lethal toxicity of Chlorpyrifos on common carp, Cyprinus carpio (Linnaeus, 1758): Biochemical response. Int J Aqua Biolo. 1(6), 281-288.
34. Al-Hammdani Y.A., Al-Baggou B.K. 2014. Study of acute toxicosis and biochemical changes induced by amitraz in chicks. Iraqi J Vet Sci. 28(2), 143-148.
35. Newman S.H., Anderson D.W., Ziccardi M.H., Trupkiewicz J.G., Tseng F.S., Christopher M.M., Zinkl J.G., 2000. An experimental soft-release of oil-spill rehabilitated American Coots (Fulica americana): II. Effects on health and blood parameters. Environ Pollut. 107, 295ââ‚‌“304.
36. Peckova L., Hana B., Klara H., Veronika D., Jana S., Frantisek V., 2009. Biochemical responses of juvenile and adult Japanese quails to cyanobacterial biomass. Neuro Endocrinol Letters. 1, 199-204.