کاربردهای نانوزیست مواد در ارتوپدی
محورهای موضوعی : شیمی و مهندسی شیمی کلیه گرایش هاسعیده ابراهیمی اصل 1 , بهزاد یثربی 2
1 - گروه شیمی، دانشکده علوم پایه، دانشگاه آزاد اسلامی واحد اهر، اهر، ایران
2 - استادیار گروه مهندسی پزشکی، دانشگاه آزاد اسلامی واحد تبریز، تبریز، ایران
کلید واژه: ارتوپدی, نانوزیست مواد , مهندسی بافت , استخوان,
چکیده مقاله :
پیشرفتهای اخیر در نانوبیوتکنولوژی، انقلابی را در توانایی ما برای درک پیچیدگیهای بیولوژیکی و حل مشکلات در حوزه پزشکی همراه با توسعه تکنیکها و مواد بیومتریک ایجاد کرده است. اعتقاد بر این است که نانوکامپوزیت ها و مواد نانوساختار با ویژگیهای خاص ساختاری و فیزیکی و شیمیایی، نقشی محوری در تحقیقات ارتوپدی ایفا می کنند، زیرا خود استخوان نمونه¬ای معمولی از نانوکامپوزیت ها است. این مقاله به بررسی تحقیقات اخیر در استفاده از نانوزیست کامپوزیتها برای بهبود مواد مورد نیاز ارتوپدی میپردازد و کاربرد آنها را در مهندسی بافت استخوان و نیز به عنوان رابط های تاندون- استخوان بررسی میکند. تحقیقات اولیه پتانسیل نانوزیست مواد را برای کاربردهای ارتوپدی نشان می¬دهد. ولیکن با توجه به گستره قابل توجه کاربردی این مواد در این حوزه و نیاز به بررسی بالینی این کامپوزیت ها تحقیقات همچنان ضروری است. لذا بررسی های بیشتری در این حوزه و کاربردهای پزشکی این مواد پیشنهاد می شود.
Recent advances in nanobiotechnology have created a revolution in our ability to understand biological complexities and solve medical problems by developing sophisticated biometric techniques and materials. It is believed that nanocomposites and nanostructured materials with special structural, physical and chemical characteristics play a central role in orthopedic research because bone itself is a typical example of nanocomposites. This article reviewed resent researches on the use of nano-biomaterials to improve orthopedic materials and their application in bone tissue engineering and tendon-bone interfaces. Preliminary research supports the potential of nanobiomaterials for orthopedic applications. However, considering the significant range of applications of these materials in this field and the need for clinical examination of these composites, research is still necessary. Therefore, more investigations in this field and medical applications of these substances are suggested.
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