Significance of Size, Surface Chemistry and Morphology in Nanodrugs Behavior: A Mini-review
محورهای موضوعی : Biotechnological Journal of Environmental Microorganisms
1 - Department of Microbiology, Faculty of Basic Sciences, Lahijan Branch, Lahijan, Iran
کلید واژه: Nanoparticle, Nanodrug, Physio-chemical properties,
چکیده مقاله :
Nanoparticles (NPs) have increasingly captured attention as high potential anticancer drugs over the years. A categorization of this landscape can immensely propel organized comparative research in the future and bring deeper understanding of nanomaterials’ comportment in biological settings. Although diverse, all nano platforms pursue similar goals of increasing efficacy in the four domains of oncology known as; diagnosis, treatment, drug delivery, and detection of biomarkers. In this review, we have gathered and provided a class-affiliated rendering of the most recent wet-lab research exploring the impacts of size, surface chemistry, and morphology in various aspects of cancer care. Efforts here are focused on defining parameters for physicochemical properties of NPs and demonstrating variable attributes of them with regard to each. The said goal is achieved by i) grouping NPs under parameters of size, surface properties, and shape, ii) listing major types of NP within each group, and iii) arranging diverse and well-trusted original research done on cancer control over the past years.
چکیده انگلیسی:
Nanoparticles (NPs) have increasingly captured attention as high potential anticancer drugs over the years. A categorization of this landscape can immensely propel organized comparative research in the future and bring deeper understanding of nanomaterials’ comportment in biological settings. Although diverse, all nano platforms pursue similar goals of increasing efficacy in the four domains of oncology known as; diagnosis, treatment, drug delivery, and detection of biomarkers. In this review, we have gathered and provided a class-affiliated rendering of the most recent wet-lab research exploring the impacts of size, surface chemistry, and morphology in various aspects of cancer care. Efforts here are focused on defining parameters for physicochemical properties of NPs and demonstrating variable attributes of them with regard to each. The said goal is achieved by i) grouping NPs under parameters of size, surface properties, and shape, ii) listing major types of NP within each group, and iii) arranging diverse and well-trusted original research done on cancer control over the past years.
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