Phytochemistry and biological activities of Tetracera species
محورهای موضوعی : PharmacognosyAkingbolabo Ogunlakin 1 , Mubo Sonibare 2
1 - Bowen University SDG 03 (Good Health and Wellbeing Research Cluster), Nigeria
|Phytomedicine, Molecular Toxicology, and Computational Biochemistry Research Laboratory (PMTCB-RL), Department of Biochemistry, Bowen University, Iwo, 232101, Nigeria
2 - Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria
کلید واژه: <i>Tetracera</i> species, Flavonoids, Pharmacological activities, phytochemicals, terpenoids,
چکیده مقاله :
The species of the genus Tetracera are utilized as remedies for various illnesses and infections including backache, haemorrhoids, diabetes, jaundice, scurvy, cough, and tooth pain. The root, stem bark, and leaves of these medicinal plants display several physiological activities. The phytochemicals reportedly present in the species include tannins, flavonoids, cardiac glycosides, saponins, phlobatannins, terpenoids, and flavonoids. Ethanol extract or fraction of plants in this genus mostly yielded flavonoids with significant antioxidant, anti-inflammatory, and antidiabetic activities. However, few compounds have been isolated so far from the species, which include pentacyclic lupane-type triterpene derivatives and flavonoids, of which betulinic acid remains the mostly investigated compound. This review documented up-to-date information on folkloric uses, isolated compounds, and pharmacological activities of medicinal plants in Tetracera species.
Abdullah, F., Ismail, N.H., Jamaludin, F., Hashim, S.N., 2014. Xanthine oxidase inhibitory activity of Tetracera indica. In The Open Conf. Proc. J. 4(1), 93-94
Abdullah, N.S., 2020. Antibacterial Effect of Melastoma malabathricum, Tetracera indica and Ardisia crispa Against Bacterial Isolates of Subclinical Mastitis in Dairy Cattle, Ph.D. Thesis.
Addo-Fordjour, P., Rahmad, Z.B., Shahrul, A.M., 2012. Effects of human disturbance on liana community diversity and structure in a tropical rainforest, Malaysia: Implication for conservation. J. Plant Ecol. 5(4), 391-9.
Adekunle, A.A., Duru, C., Odufuwa, O.M., 2003. Antifungal activity and phytochemical screening of the crude extracts of Khaya ivorensis Juss (Meliaceae) and Tetracera potatoria.(Dilleniaceae). S. Afr. J. Bot. 69(4), 568-71.
Adesanwo, J.K., Ekundayo, O., Oluwole, F.S., Olajide, O.A., Van Den Berge, A.J., Findlay, J.A., 2003. The effect of Tetracera potatoria and its constituent betulinic acid on gastric acid secretion and experimentally-induced gastric ulceration. Niger. J. Physiol. Sci. 18(1), 21-26.
Adesanwo, J.K., Makinde, O.O., Obafemi, C.A., 2013. Phytochemical analysis and antioxidant activity of methanol extract and betulinic acid isolated from the roots of Tetracera potatoria. J. Pharm. Res. 6(9), 903-907.
Ahmed, Q.U., Dogarai, B.B., Amiroudine, M.Z., Taher M, Latip, J., Umar, A., Muhammad, B.Y., 2012. Antidiabetic activity of the leaves of Tetracera indica Merr.(Dilleniaceae) in vivo and in vitro. J. Med. Plant Res 6(49), 5912-22.
Alhassan, A.M., Ahmed, Q.U., Latip, J., Shah, S.A., 2019. A new sulphated flavone and other phytoconstituents from the leaves of Tetracera indica Merr. and their alpha-glucosidase inhibitory activity. Nat. Prod. Res. 33(1), 1-8.
Arkinstall, W., 1979. Medicinal and useful plants collected in the Manianga district of the Republic of Zaire, Revue de recherche scientifique, Spécial Médecine traditionnelle au Zaïre. pp.135-158.
Aworinde, D.O., Erinoso, S.M., IbukunOluwa, M.R., Teniola, S.A., 2020. Herbal concoctions used in the management of some women-related health disorders in Ibadan. J. Appl. Biosci. 147, 15091-15099.
Betti, J.L., 2004. An ethnobotanical study of medicinal plants among the Baka pygmies in the Dja biosphere reserve, Cameroon. Afr. Study Monogr. 25(1), 1-27.
Birhan, Y.S., Kitaw, S.L., Alemayehu, Y.A., Mengesha, N.M., 2017. Ethnobotanical study of medicinal plants used to treat human diseases in Enarj Enawga district, East Gojjam zone, Amhara region, Ethiopia. SM J. Med. Plant Stud. 1(1), 1-20.
Boumba, L.S., Cristina, A., Ntandou, F.G., Oniga, I., Benedec, D.A., Vlase, A.M., Vostinaru, O., Abena, A.A., Mogosan, C.R., 2022. Polyphenolic profile and anti-inflammatory, analgesic and antioxidant effects of ethanolic and hydro-ethanolic extracts of Heinsia crinita afz. G. Taylor and Tetracera alnifolia Willd. Farm. Clin. 70(2), 272-8.
Bouquet, A., 1974. Plantes médicinales de la Côte d'Ivoire. Office de la Recherche Scientifique et Technique d'Outre Mer (ORSTOM), Paris.165, 38-39.
Bruniera, C.P., Groppo, M., 2010. Flora da Serra do Cipó, Minas Gerais: Dilleniaceae. Bol. Bot. Univ. São Paulo 1, 59-67.
Burkill, H.M., 1985. The useful plants of West Tropical Africa. Families AD (No. Ed. 2). Royal Botanic Gardens.
Cates, R.G., Prestwich, B., Innes, A., Rowe, M., Stanley, M., Williams, S., McDonald, S., Cates, S., Shrestha, G., Soria, J.A., Espinoza, L.V., 2013. Evaluation of the activity of Guatemalan medicinal plants against cancer cell lines and microbes. J. Med. Plant Res. 4(35), 2616-2627.
Chuakul, W., 2010. Analgesic herbs. Thai. Pharm. Health Sci. J. 5(1), 1-13.
De Lima, C.C., Lemos, R.P., Conserva, L.M., 2013. Chemical constituents, larvicidal effects and radical scavenging activity of Tetracera breyniana Schltdl.(Dilleniaceae). J. App. Pharm. Sci. 3(9), 14.
De Lima, C.C., Lemos, R.P., Conserva, L.M., 2014. Dilleniaceae family: An overview of its ethnomedicinal uses, biological and phytochemical profile. J. Pharmacogn. Phytochem. 3(2), 181-204.
Fenner, R., Betti, A.H., Mentz, L.A., Rates, S.M., 2006., Plants with potencial antifungal activity employed in Brazilian folk medicine. Rev. de Cienc. Farm. 42(3), 369-394.
Fomogne-Fodjo, M.C., Ndinteh, D.T., Olivier, D.K., Kempgens, P., Van Vuuren, S., Krause, R.W., 2017. Secondary metabolites from Tetracera potatoria stem bark with anti-mycobacterial activity. J. Ethnopharmacol. 195, 238-245.
Fomogne-Fodjo, M.C., Van Vuuren, S., Ndinteh, D.T., Krause, R.W., Olivier, D.K., 2014. Antibacterial activities of plants from Central Africa used traditionally by the Bakola pygmies for treating respiratory and tuberculosis-related symptoms. J. Ethnopharmacol. 155(1), 123-131.
Fowler, D.G., 2006. Traditional fever remedies: A list of Zambian plants. Kirkia 18(19), 35-48.
Gbadamosi, I.T., Adeyemi, S.B., Adeyemi, A.A., Moody, J.O., 2012. In vitro antisickling activities of two indigenous plant recipes in Ibadan, Nigeria. Int. J. Phytomedicine. 4(2), 205.
Gbadamosi, I.T., Oleyede, A.A., 2014. The mineral, proximate and phytochemical components of ten Nigerian medicinal plants used in the management of arthritis. Afr. J. Pharm. Pharmacol. 8(23), 638-643.
Hanum, F.A., Hamzah, N., 1999. The use of medicinal plant species by the Temuan tribe of Ayer Hitam Forest, Selangor, Peninsular Malaysia. Pertanika J. Trop. Agric. Sci. 2(2), 85-94.
Hasan, M., Ahmed, Q.U., Soad, S.Z., Latip, J., Taher, M., Syafiq, T.M., Sarian, M.N., Alhassan, A.M., Zakaria, Z.A., 2017. Flavonoids from Tetracera indica Merr. induce adipogenesis and exert glucose uptake activities in 3T3-L1 adipocyte cells. BMC Complement Altern. Med. 17(1), 1-4.
Hoogland, R.D., 1953. The genus Tetracera (Dilleniaceae) in the Eastern old world. Reinwardtia. 2(2),185-224.
Horn, J.W., 2007. Dilleniaceae. InFlowering Plants· Eudicots. Springer, Berlin, Heidelberg.
Horn, J.W., 2009. Phylogenetics of Dilleniaceae using sequence data from four plastid loci (rbcL, infA, rps4, rpl16 intron). Int. J. Plant Sci. 170(6), 794-813.
Indonesia, K.R., Hoogland, R.D., 1953. The genus Tetracera (Dilleniaceae) in the eastern old world. Herbarium Bogoriense 2(2), 185-224.
Johnny, J., Lebbie, A., Wadsworth, R., 2022. Ethnobotanical survey of medicinal plants utilized by forest edge communities in southern Sierra Leone. J. Med. Plant Res 16(1), 11-25.
Kembelo, K.A.O., 2003. Some medicinal plants of Bas-Congo and their uses. www.sie-cameroun.cm/?q=biblio/doc/4825.
Koparde, A.A., Doijad, R.C., Magdum, C.S., 2019. Natural products in drug discovery. InPharmacognosy-medicinal plants. IntechOpen.
Kwon, H.S., Park, J., Kim, J.H., You, J.C., 2012. Identification of anti-HIV and anti-reverse transcriptase activity from Tetracera scandens. BMB Rep. 45(3), 165-170.
Lawal, T.O., Adeniyi, B.A., Wan, B., Franzblau, S.G., Mahady, G.B., 2011. In-vitro susceptibility of Mycobacterium tuberculosis to extracts of Uvaria afzelli Scott Elliot and Tetracera alnifolia Willd. Afr. J. Biomed. Res. 14(1), 17-21.
Lawal, T.O., Jimoh, K.A., Adeniyi, B.A., 2014. Antimicrobial Potentials of Uvaria Afzelli Scott-Elliot and Tetracera alnifolia Willd Crude Extracts on Selected Human Pathogens: An in vitro study. J. Nat. Sci. Res. 4(6), 115.
Lee, J.A., Shin, J.Y., Hong, S.S., Cho, Y.R., Park, J.H., Seo, D.W., Oh, J.S., Kang, J.S., Lee, J.H., Ahn, E.K. 2022. Tetracera loureiri extract regulates lipopolysaccharide-induced inflammatory response via nuclear factor-κB and mitogen activated protein kinase signaling pathways. Plants 11, 284. doi.org/10.3390/plants11030284
Lee, M.S., Kim, C.H., Hoang, D.M., Kim, B.Y., Sohn, C.B, Kim, M.R., Ahn, J.S., 2009. Genistein-derivatives from Tetracera scandens stimulate glucose-uptake in L6 myotubes. Biol. Pharm. Bull. 32(3), 504-508.
Lepley, D.M., Li, B., Birt, D.F., Pelling, J.C., 1996. The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes. Carcinogenesis 17(11), 2367-2375.
Li, Z., Wei, Y., Rogers, E., 2003. Food choice of white-headed langurs in Fusui, China. Int. J. Primatol. 24(6), 1189-1205.
Ma, J., Starck, S.R., Hecht, S.M., 1999. DNA polymerase β inhibitors from Tetracera boiviniana Baill. J. Nat. Prod. 62(12), 1660-1663.
Mann, A., Gbate, M., Nda-Umar, A., 2003. Medicinal and Economic Plants of Nupe Land. Jube-Evans Books and Publications, Bida, Niger State, Nigeria.
Mazlun, M.H., Sabran, S.F., Abdullah, Z., Parumasivam, T., 2021. A Comparative Study of Antituberculosis Activities of Tetracera macrophylla Hook.f. & Thomson Wall. Ex Hook. f. &Thoms. Stem Fractions Using Different Chromatographic Stationary Phases. InIOP Conference Series: Earth and Environmental Science 736(1), 012036.
Mazlun, M.H., Sabran, S.F., Abdullah, Z., Parumasivam, T., 2021. A comparative study of antituberculosis activities of Tetracera macrophylla Hook.f. & Thomson Wall. Ex Hook. f. & Thomson. stem fractions using different chromatographic stationary phases. IOP Conf. Series: Earth Env. Sci. 736(012036), 1-8.
Mertz, H.R., Walsh, J.H., 1991. Peptic ulcer pathophysiology. Med. Clin. North Am. 75(4), 799-814.
Mohammadhosseini, M., Frezza, C., Venditti, A., Mahdavi, B., 2022. An overview of the genus Aloysia Palau (Verbenaceae): Essential oil composition, ethnobotany and biological activities. Nat. Prod. Res. 36(19), 5091-5107.
Muharni, M., Julunar, J., Yohandini, H., 2019. β-Sitosterol and betulonic acid from n-hexane extract the stem bark of Tetracera indica. Molekul 14(2), 103-109.
Muliyah, E., Sulistijorini, S., Sulistyaningsih, Y.C., Rafi, M., 2018. Tetracera scandens as a medicinal plant: Secretory structures, histochemistry, and antibacterial activity. J. Trop. Life Sci. 8(1), 228133.
Mustaqim, W.A., 2020. Wild native plants in urban ecosystems around Jakarta: A checklist of the woody species of universitas Indonesia. J. Pro-life. 7(1), 49-60.
N’Goka, V., Nicaise, N.O., Mokoko, J.B., Antheaume, C., 2020. Facile root for isolation of rhamnocitrin sulphate from Tetracera alnifolia. Adv. Anal. Chem. Instrum. 10(1), 1-6.
Nahar, L., El-Seedi, H.R., Khalifa, S.A.M., Mohammadhosseini, M., Sarker, S.D., 2021. Ruta essential oils: Composition and bioactivities. Molecules 26(16), 4766.
Nair, R.R., Suja, S.R., Aneeshkumar, A.L., Bhaskar, S., Vilash, V., Rajasekharan, S., 2020. Ameliorative effect of ethanolic extract of roots of Tetracera akara (Burm. f.) Merr. on D-galactosamine induced hepatotoxicity in Wistar rats by downregulation of inflammatory mediators like TNFα, COX-2 and iNOS. Indian J. Exp. Biol. 58, 161-71
Nair, R.R., Suja, S.R., Aneeshkumar, A.L., Vilash, V., Kumar, B.B., Rajasekharan, S., Latha, P.G., 2017. Evaluation of acute and sub-acute oral toxicity of ethanolic root extract of Tetracera akara (Burm. Fil.) Merr., an ethnomedicinal plant used by the Kani tribe of Kerala. J. Tradit. Folk Pract. 5(2), 71-85.
Nair, R.R., Suja, S.R., Vilash, V., Aneeshkumar, A.L., Rajasekharan, S., Kumar, B.B., 2019. Protective effect of ethanol extract of roots of Tetracera akara (Burm. f.) Merr., on carbon tetrachloride-induced hepatic injury in Wistar Rats. Indian J. Pharm. Sci. 81(5), 859-67.
Nguyen, M.T., Awale, S., Tezuka, Y., Le Tran, Q., Watanabe, H., Kadota, S., 2004. Xanthine oxidase inhibitory activity of Vietnamese medicinal plants. Biol. Pharm. Bull. 27(9), 1414-1421.
Nokhala, A., Ahmed, Q.U., Saleh, M.S., Nipun, T.S., Khan, A.A., Siddiqui, M.J., 2020a. Characterization of α-glucosidase inhibitory activity of Tetracera scandens leaves by Fourier transform infrared spectroscopy-based metabolomics. Adv. Trad. Med. 20(2), 169-180.
Nokhala, A., Siddiqui, M.J., 2020. Phytochemicals and biological activity of Tetracera scandens (L.) Merr. Linn. Merr.(Dilleniaceae): A short review. J. Pharm. Bioallied Sci. 12(3), 217.
Nokhala, A., Siddiqui, M.J., Ahmed, Q.U., Ahamad Bustamam, M.S., Zakaria, Z.A., 2020b. Investigation of α-glucosidase inhibitory metabolites from Tetracera scandens leaves by GC-MS metabolite profiling and docking studies. Biomolecules 10(2), 287.
Nsonde Ntandou, G.F., Boumba, L.S., Gouollaly, T., Makambila, M.C., Ouamba, J.M., Abena, A.A., 2017. Acute toxicity, anti-inflammatory and analgesic effects of aqueous extract of Tetracera alnifolia Willd.(Dilleniaceae). Res. J. Phamacol. Pharm. 1(2), 1-13.
Nursanti, N., Adriadi, A., 2019. Study of basic vegetation composition in Sultan Thaha Saifuddin grand forest park area. Media konserv. 24(1), 85-93.
Obonga, W.O., Agbo, M.O., Nnadi, C.O., Okechukwu, E.I., 2018. Ethyl acetate fraction of Tetracera alnifolia (Wild) stem extract possesses antinociceptive and anti inflammatory activities. African Int. J. Pharm. Res. Dev. 10(2), 107-114.
Ogunlakin, A.D., Sonibare, M.A., 2019. Ethnobotanical survey of medicinal plants used as remedy for female infertility and menstrual disorder in southwestern Nigeria. Niger. J. Pharm. Sci 5(1), 205-217.
Ogunlakin, A.D., Sonibare, M.A., Jabeen, A., Shaheen, F., Shah, S.F., 2021. Antiproliferative and ameliorative effects of Tetracera potatoria and its constituent. Adv. Trad. Med. 21(4), 815-24.
Okabe, S., Amagase, K., 2005. An overview of acetic acid ulcer models—The history and state of the art of peptic ulcer research—. Biol. Pharm. Bull. 28(8), 1321-1341.
Olaoluwa, O., Taiwo, O., Nahar, L., Sarker, S.D., 2022. Ethnopharmacology, phytochemistry and biological activities of selected African species of the genus Ficus. Trends Phytochem. Res. 6(1), 46-69.
Oluwole, F.S., Ayo, J.A., Omolaso, B.O., Emikpe, B.O., Adesanwo, J.K., 2008. Methanolic extract of Tetracera potatoria, an antiulcer agent increases gastric mucus secretion and endogenous antioxidants. Niger. J. Physiol. Sci. 23(1-2), 79-83.
Omotayo, F.O., Borokini, T.I., 2012. Comparative phytochemical and ethnomedicinal survey of selected medicinal plants in Nigeria. Sci. Res. Essays 7(9), 989-999.
Ong, H.C., Ahmad, N., Milow, P., 2011. Traditional medicinal plants used by the Tamuan villagers in Kampung Tering, Negeri Sembilan, Malaysia. Ethno Med. 5(3), 169-173.
Ong, H.C., Norzalina, J., 1999. Malay herbal medicine in Gemencheh, Negri Sembilan, Malaysia. Fitoterapia 70(1), 10-14.
Opara, E.R., Osayi, K.K., 2016. Factors affecting the utilization of herbal medicine as a livelihood alternative among residents of Imo State: The role of social work professionals. Int. J. Humanit. Soc. Sci. 21(5), 66-78.
Oyebanji, B., Saba, A.B., 2011. Phytochemistry and in vitro anti-oxidant activities of Stellaria media, Cajanus cajan and Tetracera potatoria methanolic extracts. J. Med. Plant Res. 5(30), 6622-6627.
Oyebanji, B.O., Saba, A.B., Oridupa, O.A., 2013. Antinociceptive and anti-inflammatory activities of methanol root extract of Tetracera potatoria. Afr. J. Biomed. Res 16(3), 199-204.
Oyebanji, B.O., Saba, A.B., Oridupa, O.A., 2014. Studies on the anti-inflammatory, analgesic and antipyrexic activities of betulinic acid derived from Tetracera potatoria. Afr. J. Tradit. Complement. Altern. Med. 11(1), 30-3.
Ozturk, M., Altay, V., Latiff, A., Shareef, S., Shaheen, F., Iqbal Choudhry, M., 2018. Potential medicinal plants used in the hypertension in Turkey, Pakistan, and Malaysia. InPlant and Human Health 1, Vol. 1. Springer, Cham, 595-618.
Pardo, De T., 2008. Medicinal Plants of Philippines. Ebook, Jeroen Hellingman.
Pejin, B., Bianco, A., Newmaster, S., Sabovljevic, M., Vujisic, L., Tesevic, V., Vajs, V., De Rosa, S., 2012. Fatty acids of Rhodobryum ontariense (Bryaceae). Nat. Prod. Res. 26(8), 696-702.
Pejin, B., Vujisic, L., Sabovljevic, M., Tesevic, V., Vajs, V., 2011. Preliminary data on essential oil composition of the moss Rhodobryum ontariense Kindb. Cryptogam. Bryol. 32(2), 113-117.
Purkayastha, J., Dutta, M., Nath, S.C., 2007. Ethnomedicinal plants from Dibru-Saikhowa biosphere reserve, Assam. Indian J. Tradit. Knowl. 6(3), 477-480.
Putz, F.E., Chai, P., 1987. Ecological studies of lianas in Lambir national park, Sarawak, Malaysia. J. Ecol. 1, 523-31.
Quattrocchi, U., 2012. CRC World Dictionary of Medicinal and Poisonous Plants: Common Names, Scientific Names, Eponyms, Synonyms, and Etymology, Taylor & Francis Group Vol. 5. CRC Press, Boca Raton, FL, pp. 3251-3645.
Roheem, F.O., 2018. Phytochemicals From Entada spiralis Ridl. and Tetracera macrophylla Vall. and Their Bioactivities, Ph.D. Thesis.
Roheem, F.O., Ahmed, Q.U., So'ad, S.M., Shah, S.A., Latip, J., Alhassan, A.M., Mohammad, S.S., 2020. Assessment of free radical scavenging and digestive enzyme inhibitory activities of extract, fractions and isolated compounds from Tetracera macrophylla leaves. J. Herbal Med. 22(2020), 100351.
Rustiami, H., 2016. Index reinwardtia. Reinwardtia 15(2), 137-140.
Sabran, S.F., Mohamed, M., Abu Bakar, M.F., 2016. Ethnomedical knowledge of plants used for the treatment of tuberculosis in Johor, Malaysia. Evid. Based Complement Alternat Med. 2016, 2850845, doi: 10.1155/2016/2850845.
Sari, R., Astuti, I.P., Susandarini, R., Makmur, I., 2020. The plant species diversity of Lasitae protected nature forest and nearby area, District of Barru, South Sulawesi. J. Trop. Biodivers. Biotechnol. 5(2), 89-99.
Setiawati, T., Ayalla, A., Nurzaman, M., Mutaqin, A.Z., 2018. Influence of Light Intensity on Leaf Photosynthetic Traits and Alkaloid Content of Kiasahan (Tetracera scandens). In IOP Conference Series: Earth and Environmental Science 166(1), 012025.
Souza, R.P., Bonfim-Mendonça, P.D., Gimenes, F., Ratti, B.A., Kaplum, V., Bruschi, M.L., Nakamura, C.V., Silva, SO., Maria-Engler, S.S., Consolaro, M.E., 2017. Oxidative stress triggered by apigenin induces apoptosis in a comprehensive panel of human cervical cancer-derived cell lines. Oxid. Med. Cell. Longev., doi: 10.1155/2017/1512745.
Sritubtim, S., Krapeedeang, S., Wongsa, N., 2014. Biological activities on growth inhibition of bacteria of medicinal plant extracts from plants found in the upper Northeastern Thailand. SDU Res. J. 7(1), 21-39.
Stangeland, T., Alele, P.E., Katuura, E., Lye, K.A., 2011. Plants used to treat malaria in Nyakayojo sub-county, western Uganda. J. Ethnopharmacol. 137(1), 154-166.
Subramanyam, R., Goud, M., Sudhamalla, B., Reddeem, E., Gollapudi, A., Nellaepalli, S., Yadavalli, V., Chinnaboina, M., Amooru, D.G., 2009. Novel binding studies of human serum albumin with trans-feruloyl maslinic acid. J. Photochem. Photobiol. B: Biol. 95(2), 81-88.
Süntar, I., 2020. Importance of ethnopharmacological studies in drug discovery: Role of medicinal plants. Phytochem. Rev. 19(5), 1199-209
Tawan, C.S., 2021. Tetracera scandens (L.) Merr. (L.) Merr. Plant Resources of South-East Asia. 2001(12), 2.
Thagriki, D.S., Ray, U., 2022. An overview of traditional medicinal plants as dengue virus inhibitors. Trends Phytochem. Res. 6(2), 116-136.
Tona, L., Cimanga, R.K., Mesia, K., Musuamba, C.T., De Bruyne, T., Apers, S., Hernans, N., Van Miert, S., Pieters, L., Totté, J., Vlietinck, A.J., 2004. In vitro antiplasmodial activity of extracts and fractions from seven medicinal plants used in the Democratic Republic of Congo. J. Ethnopharmacol. 93(1), 27-32.
Uddin Mazumdar, M.M., Islam, M.A., Hosen, M.T., Alam, M.S., Alam, M.N., Faruk, M., Rahman, M.M., Sayeed, M.A., Rahman, M.M., Uddin, S.B., 2017. Estimation of in vivo neuropharmacological and in vitro antioxidant effects of Tetracera sarmentosa. Cogent Biol. 3(1), 1300990.
Umar, A., Ahmed, Q.U., Muhammad, B.Y., Dogarai, B.B., Soad, S.Z., 2010. Anti-hyperglycemic activity of the leaves of Tetracera scandens Merr.(Dilleniaceae) in alloxan induced diabetic rats. J. Ethnopharmacol. 131(1), 140-5.
Useful Tropical Plants, 2019. Available from: http://tropical.theferns.info/viewtropical.php?id=Tetracera+scandens.
Wadhwa, B.M., 2017. Dilleniaceae. In A Revised Handbook to the Flora of Ceylon. Routledge, pp. 109-135.
World Health Organisation., 2008. Traditional, complementary and integrative medicine. https://www.who.int/health-topics/traditional-complementary-and-integrative-medicine#tab=tab_1. Accessed on 15-4-2022.
Xie, P., Liu, T., Chen, H., Su, Z., 2021. Community structure and soil mineral concentration in relation to plant invasion in a subtropical urban and rural ecotone. Forests 12(2), 185.
You, J.C., 2015. Antiviral Compositions Comprising Ethanol, Extract of Tetracera scandens and Use Thereof. United States Patent. Patent No.: Us 9,084,758 B2. Jul. 21, 2015.