اثرتمرینات TRX بر سطوح نیتریک اکساید و هموسیستئین به عنوان شاخص-های اندوتلیال عروق و التهاب در زنان چاق غیر فعال

محورهای موضوعی : مجله پلاسما و نشانگرهای زیستی

شیما قره داشخانی گرده ¹ , عبدالعلی بنایی فر ² , سعید صداقتی ³ , یاسر کاظم زاده ⁴ , کیوان ملانوروزی ⁵

1 - دانشجوی دکتری فیزیولوژی ورزش دانشکده تربیت بدنی - دانشگاه آزاد اسلامی واحد اسلام شهر
2 - دانشیار، گروه فیزیولوژی ورزشی، دانشگاه آزاد اسلامی، واحد تهران جنوب، تهران، ایران.
3 - دانشکده تربیت بدنی - دانشگاه آزاد اسلامی واحد اسلام شهر
4 - استاد یار دانشکده تربیت بدنی دانشگاه آزاد اسلامی واحد اسلام شهر
5 - استاد یار دانشکده تربیت بدنی دانشگاه آزاد اسلامی واحد اسلام شهر

تاریخ دریافت : 1401/04/14 تاریخ پذیرش : 1401/09/26 تاریخ انتشار : 1401/10/01

کلید واژه: نیتریک اکساید, زنان چاق, تمرینات TRX, هموسیستئین,

چکیده مقاله :

زمینه و هدف: مطالعات جدید نشان می دهند چاقی در بروز التهاب نقش موثری دارد، از طرفی التهاب خود می تواند عملکرد اندوتلیال عروق را تحت تاثیر قرار دهد. مقادیر بالای هموسیستئین می تواند منجر به ایجاد التهاب و آسیب اندوتلیوم عروقی گردد. همچنین نیتریک اکساید نیز به عنوان یکی از عوامل تاثیر گذار بر عملکرد اندوتلیال مورد توجه می باشد. مطالعه حاضر با هدف تعیین اثر 8هفته تمرینات TRX بر سطوح هموسیستئین ((Hcy و نیتریک اکساید ((NO در زنان چاق غیرفعال انجام گرفته است.مواد و روش ها: در این مطالعه نیمه تجربی، 28 زن چاق بـا میـانگین سـنی: 82/0±34/44 سـال بطور تصادفی در دو گروه TRX (16نفر)و کنترل (16نفر) قرار گرفتند. برنامه گروه تجربی شامل تمرین TRX به مدت هشت هفته و سـه روز در هفتـه به مدت 60-50 دقیقه انجـام شد. مقادیر سرمی هموسیستئین ، نیتریک اکساید قبل و 48 ساعت بعد از آخرین جلسه تمرینات اندازه گیری شد. از آزمونهای تی مستقل و وابسته جهت بررسی اختلاف بین گروهها و تغییـرات درون گروهی استفاده شد.نتایج: پس از انجام هشت هفته تمرینات TRX نتایج مقایسه های درون گروهی و بین گروهی نشان داد میانگیـن شاخص هموسیستئین در گروه تمرین نسبت به گروه کنترل کاهش معنی داری داشت (p=0.01)، هر چند اثر تمرینات بر سطح نیتریک اکساید معنی داری نبود.نتیجه گیری: براساس یافته های پژوهش به نظر می رسد، انجام تمرینات TRX می تواند به عنوان یک شیوه تمرینی در کاهش التهاب و بهبود عملکرد اندوتلیال در زنان چاق موثر باشد.

چکیده انگلیسی:

Introduction & Objective:  Recent studies suggest that obesity plays an effective role in the occurrence of inflammation; on the other hand, inflammation can affect on function of vascular endothelium. High levels of homocysteine ​​can lead to inflammation and vascular endothelium damage. Nitric oxide is also considered as one of the influencing factors on endothelial function. The present study was conducted with the aim of determining the effect of 8 weeks of TRX training on the levels of homocysteine ​​(Hcy) and nitric oxide (NO) in inactive obese women. Material and Methods: In this quasi-experimental study, 28 obese women with a mean age of 44.34 ±0.82 years were randomly divided into TRX (n = 16) and control (n = 16) groups. The experimental group program consisted of TRX training for eight weeks and three days a week for 50-60 minutes. Serum levels of homocysteine, nitric oxide were measured before and 48 hours after the last training session. Independent and dependent t-tests were used to examine the differences between groups and within-group changes. Result:After eight weeks of TRX training, comparison results within and between groups are displayed that the mean homocysteine index in the exercise group decreased significantly compared to the control group (p = 0.01). Also, exercise led to an increase in nitric oxide levels in obese women, although this increase was not statistically significant. Conclusion: Based on the findings of the research, it seems that doing TRX training can be effective as an exercise method in reducing inflammation and improving endothelial function in obese women.

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