Obesity is at epidemic proportions in the world. Evidence supports increased physical activity and exercise are efficacious in controlling obesity, in part due to altering select adipocytokine levels. The present study aimed to compare the effect of 12 weeks of three resistance training methods (traditional, circular and interval) on the levels of the adipocytokine asprosin and body composition in sedentary men with obesity. Forty-four sedentary men with obesity, who were randomly divided into the 4 equal groups: traditional, circular, and interval resistance training as well as a control group. Results showed that there was a significant interaction between the type of training used and time on asprosin levels (F (1,40)= 13353.03, P= 0.001, ES= 0.99). All types of resistance training decreased asprosin levels and improved body composition parameters in comparison to the control group (F (3, 40) = 34.60, P = 0.001, ES= 0.77). Interval resistance training had the greatest effect on reducing asprosin levels and improving body composition related outcomes (body mass: P=0.001, ES=0.633, body mass index: P=0.001, ES=0.632, percent body fat: P=0.001, ES=0.647, waist to hip ratio: P=0.001, ES=0.786). The results of the present study support the benefits of resistance training as a non-pharmacological approach in reducing asprosin levels and improving body composition in individuals with obesity. تفاصيل المقالة