At the beginning of 2020, a new coronavirus, namely SARS-CoV-2, has started to spread worldwide leading to the so-called COVID-19 pandemic. The present study aims to review the effectiveness of disinfectants in the prevention and control of the COVID-19 pandemic. In this article, after an introduction to the COVID-19 pandemic, the role of disinfectants in the prevention and control of the COVID-19 pandemic is discussed. To identify the articles, English databases including Google Scholar, Scopus, Science Direct, Web of Science, and PubMed from December 2020 to November 2020 were examined using keywords. There is also a manual search in journals, a collection of abstracts in conferences, and conferences and dissertations. Hand hygiene is a well-accepted principle in preventing the transmission of most infectious diseases. Given that many formulations of sanitizers can be effective against COVID-19, it may alter the integrity and function of the skin barrier and increase the risk of dermatitis on the hands. تفاصيل المقالة