The effect of eight weeks of high intensity interval and moderate intensity continuous trainings along with Citrus Aurantium on bone alkaline phosphatase and osteocalcin in the femur tissue of elderly female rats

Subject Areas : Effects of Movement and Exercise in Health

Fatemeh Farkhaie ¹ , سعید کشاورز ² , Elham Eftekhari ³ , سید علی حسینی ⁴

1 - Department of Sports Physiology, Najafabad Branch, Islamic Azad University, Isfahan, Iran
2 - دانشگاه آزاد نجف آباد
3 - Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Isfahan, Iran
4 - گروه مدیریت ورزش، واحد مرودشت، دانشگاه آزاد اسلامی، مرودشت، ایران.

Received: 2024-04-24 Accepted : 2024-05-17 Published : 2024-06-20

Keywords: Exercise, Citrus Aurantium, Bone, Aging,

Abstract :

Background and Purpose: Osteoporosis in old age is one of the most common metabolic bone diseases. Therefore, the aim of this study is to investigate the effect of eight weeks of high intensity interval training (HIIT) and moderate intensity continuous training (MICT) along with Citrus Aurantium (CA) on bone alkaline phosphatase (BALP) and osteocalcin (OCN) in the femur tissue of elderly female rats. Material and Methods: In this experimental study, 42 elderly female rats were randomly divided into 7 groups including 1) control (C), 2) MICT, 3) HIIT, 4) MICT+CA, 5) HIIT+ CA, 6) CA and 7) Sham (normal-saline). HIIT trainings were performed with an intensity of 85- 110% VO2max and MICT trainings were performed with an intensity of 65% VO2max; CA was consumed 300 mg/kg/day. Results: In the CA, MICT, HIITHIIT+CA and MICT+CA groups, BALP and OCN levels were higher than C group (P=0.001). In addition, BALP levels in MICT+CA group were higher than CA, HIIT, MICT and HIIT+CA groups. OCN levels in the MICT group were higher than the HIIT group (P=0.001). While in the HIIT and MICT group were higher than the HIIT+CA and MICT+CA groups (P=0.001). Conclusion: It seems that although HIIT, MICT and CA are effective (both alone and interactively) in improving bone metabolism, the effect of training is much stronger than the effects of CA on osteoporosis.

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