مطالعه وضعیت سرمی پروتئین شوک حرارتی 27، آدنوزین دِآمیناز، هموسیستئین و پروفایل‌های لیپیدی در لپتوسپیروز گاوی در استان کردستان
محورهای موضوعی :
آسیب شناسی درمانگاهی دامپزشکی
کاوه عظیم زاده
1
(استادیار گروه علوم درمانگاهی، واحد اورمیه، دانشگاه آزاد اسلامی، اورمیه، ایران.)
تاریخ دریافت : 1394/06/08
تاریخ پذیرش : 1394/07/27
تاریخ انتشار : 1394/06/01
کلید واژه:
استان کردستان,
لپتوسپیروز گاوی,
پارامترهای بیوشیمیایی,
چکیده مقاله :
هدف از مطالعه حاضر ارزیابی تغییرات تعدادی از پارامترهای سرمی اعم از آدنوزین دآمیناز (ADA)، پروتئین شوک حرارتی 27 (HSP-27)، هموسیستئین (Hcy) و پروفایل لیپیدی (VLDL، Triglyceride، HDL-C، LDL-C) در لپتوسپیروز گاوی می باشد. پس از تشخیص لپتوسپیروز حاد در گاو، نمونه خون از ورید وداج 12 گاو مبتلا به لپتوسپیروز و 12 نمونه سالم اخذ شد و پارامترهای فوق الذکر همراه با روی (Zn2+) مورد اندازه گیری قرار گرفتند. نتایج، افزایش معنی دار (01/0p<) هموسیستئین، HSP-27، TG و VLDL همراه با کاهش قابل توجهHDL-C،ADA ،LDL-C و روی (Zn2+) را در گاوان بیمار در مقایسه با گروه سالم نشان دادند. بر اساس نتایج به دست آمده احتمالاً بتوان از پارامترهای ذکر شده در مدیریت بیماری لپتوسپیروز گاوی استفاده نمود.
چکیده انگلیسی:
The aim of this study was to investigate changes of serum parameters such as adenosine deaminase (ADA), heat shock protein-27 (HSP-27), homocysteine (Hcy) and lipid profiles (LDL,HDL,VLDL and Triglyceride) in bovine leptospirosis. After diagnosis of acute leptospirosis in cattle, blood samples were collected from 12 cases of bovine leptospirosis and 12 healthy samples via jugular vein and all parameters along with zinc (Zn2+) were measured. The results denoted a significant increase in Hcy, HSP-27, TG, VLDL, along with a significant decrease in HDL-C, ADA, LDL-C and zinc (Zn2+) in patients compared to healthy ones (p≤0.01). Based on the results, the listed parameters may be used in the management of bovine leptospirosis.
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