Today, the automotive industry is considered one of the strategic options for economic development. This industry plays an important role in the economic cycle of countries and has a special place in the world financial services industry. One of the most important competitive tools in this industry is the impact of macro variables on production profitability. The purpose of this study is to investigate the effect of fluctuations in economic variables affecting the profitability of IranKhodro Manufacturing Company. In this study, to test the hypotheses, the information of IranKhodro's high-circulation cars in the period between 2013-2019 was used. Independent research variables include exchange rate, inflation rate, order price, and imported cars. After calculating the required variables, a composite data regression model was used to test the hypotheses. To choose between the methods of combined regression patterns and panel data patterns, the Limer F test was used. The panel data method was selected and it was necessary to perform the Hausman test, which also confirmed the use of a fixed-effects pattern. The results of the research hypotheses showed that there is a significant relationship between exchange rate trends, inflation rate, mandatory (mandatory) pricing and imported cars, and the profitability of IranKhodro's high-volume products. پرونده مقاله