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رقم المقالة : JFST-2201-1772 (R1) زيارة : 172 الصفحة: 17 - 30

10.30495/jfst.2022.1949356.1772

نوع المخطوط: ابحاث

نوشیدنی فراسودمند ترکیبی‌حاوی عصاره‌هایگیاهان خانواده چلیپائیان جهت بهبود سیستم ایمنی

الموضوعات :

زهرا لطیفی 1 , سعید عابدیان کناری 2 , علی اکبر مشایخ 3

1 - دانشجوی دکتری،گروه علوم و‌صنایع‌غذایی، واحد نور، دانشگاه آزاد اسلامی، نور، ایران
2 - استاد،‌ ایمنی‌شناسی پزشکی، دانشکده پزشکی، دانشگاه علوم پزشکیمازندران، ساری، ایران.
3 - استادیار، گروه‌تربیت بدنی و‌علوم ورزشی، دانشکده علوم انسانی و اجتماعی، واحد نور، دانشگاه آزاد‌اسلامی، نور، ایران.

تاريخ الإرسال : 05 السبت , جمادى الثانية, 1443 تاريخ التأكيد : 04 الإثنين , شعبان, 1443 تاريخ الإصدار : 30 السبت , ذو الحجة, 1445

الکلمات المفتاحية: سیستم ایمنی, عصاره گیاهی, ظرفیت آنتی‌اکسیدانی, گیاهان چلیپائیان, خواص فیتوشیمیایی,

ملخص المقالة :

سیستم ایمنی بدن ارتباط تنگاتنگی با سلامت انسان دارد. بر این اساس، غذاهای فراسودمند حاوی ترکیبات فعال زیستی می‌توانند به‌عنوان بهبود دهنده سیستم ایمنی محسوب ‌شوند. هدف از مطالعه حاضر تولید نوشیدنی فراسودمند ترکیبی، حاوی عصاره‌های گیاهان خانواده چلیپائیان (کلم سفید، کلم قرمز، کلم بروکلی و گل کلم) جهت بهبود سیستم ایمنی می باشد. بدین منظور عصاره‌های هیدرواتانولی (70 درصد) از چهار گونه کلم تهیه شد، سپس میزان ترکیبات فنولی و فلاونوئید کل و ظرفیت آنتی-اکسیدانی به روش DPPH بررسی گردید. سپس نوشیدنی‌هایی ترکیبی از چهار عصاره با غلظت های g/ml 400 و 800 تهیه گردید و موش‌های آزمایشگاهی با دوز یک سی‌سی، طی 15 روز متوالی تغذیه شدند. سیستم ایمنی با بررسی فاکتورهای IgG، IFN-γ، IL-4، IL-10 و IL-17 توسط روش الایزای غیر رقابتی ارزیابی شد. نتایج بدست آمده حاکی از بالا بودن فنل (mg GA/g 024/063/1) و فلاونوئید تام (mg QE/g 004/0426/0) در عصاره هیدرواتانولی کلم سفید بود. همچنین در روش DPPH، بالاترین میزان مهار کنندگی رادیکال آزاد مربوط به کلم قرمز به مقدار 26/98 درصد در غلظت g/ml 800 بود. نتایج ارزیابی سیستم ایمنی نشان داد که سه فاکتور IgG، IL-10 و IL-17 در موش‌ها، با مصرف نوشیدنی فراسودمند حاوی غلظت عصاره g/ml 800 افزایش یافت؛ به‌طوری که فاکتور IgG در گروه شاهد برابر با mg/ml 68/681/10 و در گروه سوم با غلظت عصاره g/ml 800 به mg/ml 86/2035/27 افزایش یافت. نتایج نشان داد که عصاره گیاهان خانواده چلیپائیان واجد پتانسیل بالایی برای استفاده در محصولات غذایی با هدف افزایش کیفیت و ارزش تغذیه ای را دارند.

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