یکارگیری فعالیت های ورزشی به عنوان روش غیر دارویی می تواند در فرایند تولید پادزهر و حفظ و ارتقا سلامت دام نقش مهمّی را ایفا کند. هدف از پژوهش حاضر، بررسی اثرات تمرین هوازی بر بیان اینترفرون گاما و زیر رده های لکوسیتی در روند تولید پادزهر بود. بدین منظور، 10 رأس اسب نژاد مخلوط بالغ 8- 5 ساله با میانگین وزنی350-300 کیلوگرم در چرخه تولید پادزهر به صورت تصادفی به دو گروه زهر (V) و گروه زهر + تمرین (TV) تقسیم شدند. گروه آزمایشی، برنامه تمرینات هوازی را به مدّت 22 هفته، 3 جلسه در هفته و حداکثر زمان 30 دقیقه با شدت 50-60 درصد ماکزیمم ضربان قلب انجام داد. از آزمودنی های هر دو گروه در دو نوبت، قبل از شروع و پایان پروتکل از طریق سیاهرگ وداج خون گیری به عمل آمد.نتایج تحقیق نشان داد، تعداد گلبول های سفید و لنفوسیت ها، نسبت به سطوح پایه کاهش یافت. از سوی دیگر تعداد مونوسیت ها و نوتروفیل ها روند افزایشی را نشان داد، که این افزایش در هیچ کدام از متغییرها معنادار نبود. همچنین میزان اینترفرون گاما نسبت به سطوح پایه کاهش یافت ولی این کاهش معنادار نبود. در مجموع نتایج تحقیق حاضر نشان داد یک دوره تمرین استقامتی 22 هفته ای می تواند در میزان اینترفرون گاما و زیر رده های لکوسیتی به منظور حفظ و ارتقاء سلامت دام تغییر ایجاد کند ولی جهت معنادار بودن تغییرات این شدّت از تمرینات تأثیرات معناداری را در تعدیل تغییرات ایمونولوژیکی در گروه تمرین نداشته است. تفاصيل المقالة

Introduction: In different studies, the effects of exercise and mental stress on electrical waves of the heart have been investigated separately. Nonetheless, the aim of this study was to investigate the simultaneous effect of exercise with mental stress on changes in electrical waves of the heart of young men. Methods: 24 healthy inactive men were selected and randomly divided into two groups of exercise and exercise with mental stress. The subjects in the exercise group biked for 37 minutes (60 % of the maximum aerobic capacity), and the subjects in the exercise with mental stress, biked for 37 minutes while they received 20 minutes of mental stress during biking, from minute 10 to 32. Heart electrocardiogram was recorded at 6 stages of resting, before exercise, 10, 20, 32 and 37 minutes since exercising. Statistical analysis was performed using ANOVA with repeated measures at a significant level of 0.05. Results: No significant difference in heart rate changes (p = 0.71), QRS voltage changes (P = 0.41), QT changes (P = 0.57), QTc changes (P = 0.54) ST segment changes (P = 0.053) and R-R interval changes (P = 0.58) were observed in the interactive effect of group and time. Conclusion: The pattern of changes in the electrical waves of the heart applied in this study was similar in two groups of moderate intensity exercise with mental stress and without mental stress. Keywords: Exercise, Heart, Mental Stress تفاصيل المقالة

Introduction: Diabetes is a metabolic disease that has a close relationship with increased physical disabilities and muscle tissue damage. The aim of this study was to investigate the effect of interval and continued trainings with crocin consumption on Bcl-2, Bax and P53 gene expression of heart tissue in high-fat diet- and streptozotocin induced type 2 diabetic rats. Methods: In this experimental study, 49 adult high-fat diet- and streptozotocin induced diabetic rats were selected and randomly assigned to 7 groups (1) high intensity interval training (HIIT) (2) low intensity continued training (LICT) (3) HIIT with crocin consumption, (4) LICT with crocin consumption, (5) crocin consumption, (6) sham and (7) control. HIIT and LICT groups ran the treadmill for eight weeks, three sessions per week with intensity 80- 85 and 50- 55 percent of maximum running speed, respectively, and crocin consumption groups received crocin 25 mg/kg per week for eight weeks. To analyze the research findings, paired sample t-test, two- way ANOVA with Bonferroni post hoc test were used (p≤0.05). Results: Eight weeks of HIIT and LICT had significant effect on reduction of Bax gene expression in heart tissue of diabetic rats (p≤0.05), and HIIT had significant effect on reduction of P53 gene expression in heart tissue of diabetic rats (p≤0.05), crocin consumption had significant effect on reduction of P53 gene expression in heart tissue of diabetic rats (p≤0.05), endurance training with crocin consumption had interaction effect on increase of Bcl-2 gene expression and reduction of P53 gene expression in heart tissue of diabetic rats (p≤0.05). Conclusion: It seems that interval and continued with crocin consumption in high- fat diet- and streptozotocin induced diabetic rats have interaction anti-apoptotic effects. تفاصيل المقالة